Tout voire


Articles de journaux


Majzoub, Karim; Hafirassou, Mohamed Lamine ; Meignin, Carine ; Goto, Akira ; Marzi, Stefano ; Fedorova, Antonina ; Verdier, Yann ; Vinh, Joëlle ; Hoffmann, Jules A; Martin, Franck ; Baumert, Thomas F; Schuster, Catherine ; Imler, Jean-Luc

RACK1 controls IRES-mediated translation of viruses Article de journal

Cell, 159 (5), p. 1086–1095, 2014, ISSN: 1097-4172.

Résumé | Liens | BibTeX | Étiquettes: Cell Line, Cell Surface, Cytoplasmic and Nuclear, Dicistroviridae, GTP-Binding Proteins, Hepacivirus, Hepatocytes, Humans, Insect Viruses, Models, Molecular, Neoplasm Proteins, Peptide Initiation Factors, Protein Biosynthesis, Receptors, Regulatory Sequences, Ribonucleic Acid, Tumor, Virus Replication


Articles de journaux


Fukuyama, Hidehiro; Verdier, Yann; Guan, Yongsheng; Makino-Okamura, Chieko; Shilova, Victoria; Liu, Xi; Maksoud, Elie; Matsubayashi, Jun; Haddad, Iman; Spirohn, Kerstin; Ono, Kenichiro; Hetru, Charles; Rossier, Jean; Ideker, Trey; Boutros, Michael; Vinh, Joëlle; Hoffmann, Jules A

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge Article de journal

Proc. Natl. Acad. Sci. U.S.A., 110 (26), p. 10717–10722, 2013, ISSN: 1091-6490.

Résumé | Liens | BibTeX | Étiquettes: Amino Acid, Chromatin Assembly and Disassembly, Escherichia coli, functional proteomics, Genes, Genetically Modified, Histone Acetyltransferases, Host-Pathogen Interactions, Humans, IMD interactome, Insect, Models, Molecular, Protein Interaction Maps, Sequence Homology, Signal Transduction, small ubiquitin-like modifier


Baron, Olga Lucia; van West, Pieter; Industri, Benoit; Ponchet, Michel; Dubreuil, Géraldine; Gourbal, Benjamin; Reichhart, Jean-Marc; Coustau, Christine

Parental transfer of the antimicrobial protein LBP/BPI protects Biomphalaria glabrata eggs against oomycete infections Article de journal

PLoS Pathog., 9 (12), p. e1003792, 2013, ISSN: 1553-7374.

Résumé | Liens | BibTeX | Étiquettes: Acute-Phase Proteins, Antimicrobial Cationic Peptides, Biomphalaria, Blood Proteins, Carrier Proteins, Cell Membrane, Cell Membrane Permeability, Cloning, Escherichia coli, Female, Immunity, Infection, Maternally-Acquired, Membrane Glycoproteins, Microbial Sensitivity Tests, Molecular, Oomycetes, Recombinant Proteins, Zygote


Articles de journaux


Aoun, Richard Bou; Hetru, Charles; Troxler, Laurent; Doucet, Daniel; Ferrandon, Dominique; Matt, Nicolas

Analysis of thioester-containing proteins during the innate immune response of Drosophila melanogaster Article de journal

J Innate Immun, 3 (1), p. 52–64, 2011, ISSN: 1662-8128.

Résumé | Liens | BibTeX | Étiquettes: bioinformatic, DNA, Evolution, Gene Expression Regulation, Hemocytes, Immunity, In Situ Hybridization, Innate, Molecular, Mutation, Phylogeny, Sequence Analysis


Articles de journaux


Kemp, Cordula; Imler, Jean-Luc

Antiviral immunity in drosophila Article de journal

Current Opinion in Immunology, 21 (1), p. 3–9, 2009, ISSN: 1879-0372.

Résumé | Liens | BibTeX | Étiquettes: Argonaute Proteins, Caspases, DEAD-box RNA Helicases, Evolution, Gene Expression Regulation, Host-Pathogen Interactions, Membrane Proteins, Molecular, Nuclear Proteins, Ribonuclease III, RNA, RNA Helicases, RNA Interference, RNA Virus Infections, RNA Viruses, RNA-Induced Silencing Complex, Viral, Virulence


Garrett, Matthew; Fullaondo, Ane; Troxler, Laurent; Micklem, Gos; Gubb, David

Identification and analysis of serpin-family genes by homology and synteny across the 12 sequenced Drosophilid genomes Article de journal

BMC Genomics, 10 , p. 489, 2009, ISSN: 1471-2164.

Résumé | Liens | BibTeX | Étiquettes: bioinformatic, Comparative Genomic Hybridization, Conserved Sequence, DNA, Drosophilidae, Evolution, Genome, Insect, Molecular, Multigene Family, Sequence Alignment, Sequence Analysis, Serpins, Synteny


Articles de journaux


Croker, Ben; Crozat, Karine; Berger, Michael; Xia, Yu; Sovath, Sosathya; Schaffer, Lana; Eleftherianos, Ioannis; Imler, Jean-Luc; Beutler, Bruce

ATP-sensitive potassium channels mediate survival during infection in mammals and insects Article de journal

Nature Genetics, 39 (12), p. 1453–1460, 2007, ISSN: 1546-1718.

Résumé | Liens | BibTeX | Étiquettes: ATP-Binding Cassette Transporters, Cloning, Coronary Vessels, Crosses, Ethylnitrosourea, Genetic, Homozygote, Infection, Inwardly Rectifying, KATP Channels, Lipopolysaccharides, Mice, Molecular, Mutagenesis, Potassium Channels, Sulfonylurea Receptors


Articles de journaux


Blandin, Stephanie A; Shiao, Shin-Hong; Moita, Luis F; Janse, Chris J; Waters, Andrew P; Kafatos, Fotis C; Levashina, Elena A

Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae Article de journal

Cell, 116 (5), p. 661–670, 2004, ISSN: 0092-8674.

Résumé | BibTeX | Étiquettes: Anopheles, Female, Genetic, Humans, Insect Proteins, Insect Vectors, Malaria, Models, Molecular, Plasmodium berghei, Polymorphism, Protein Structure, RNA, Sequence Alignment, Tertiary


Articles de journaux


Luna, C; Hoa, N T; Zhang, J; Kanzok, S M; Brown, S E; Imler, Jean-Luc; Knudson, D L; Zheng, L

Characterization of three Toll-like genes from mosquito Aedes aegypti Article de journal

Insect Molecular Biology, 12 (1), p. 67–74, 2003, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Aedes, Base Sequence, Cell Surface, Chimera, Cloning, Developmental, Female, Gene Expression Regulation, Genetic, Insect Proteins, Male, Messenger, Models, Molecular, Mutagenesis, Promoter Regions, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Sequence Alignment, Signal Transduction, Site-Directed, Transfection


Articles de journaux


Levashina, Elena A; Moita, L F; Blandin, Stéphanie A; Vriend, G; Lagueux, Marie; Kafatos, F C

Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae Article de journal

Cell, 104 (5), p. 709–718, 2001, ISSN: 0092-8674.

Résumé | BibTeX | Étiquettes: alpha-Macroglobulins, Anopheles, Cells, Cloning, Complement C3, Cultured, DNA Fragmentation, Double-Stranded, Female, Genetic, Gram-Negative Bacteria, Hemocytes, Insect Proteins, Molecular, Nucleic Acid Denaturation, Phagocytosis, Protein Structure, RNA, Tertiary, Transcription


Articles de journaux


Lowenberger, C A; Smartt, C T; Bulet, Philippe; Ferdig, M T; Severson, D W; Hoffmann, Jules A; Christensen, B M

Insect immunity: molecular cloning, expression, and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti Article de journal

Insect Mol. Biol., 8 (1), p. 107–118, 1999, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Aedes, Amino Acid, Base Sequence, Blotting, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Hemolymph, Molecular, Northern, Protein Isoforms, Proteins, Sequence Homology


Articles de journaux


Uttenweiler-Joseph, S; Moniatte, M; Lagueux, Marie; Dorsselaer, Van A; Hoffmann, Jules A; Bulet, Philippe

Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study Article de journal

Proc. Natl. Acad. Sci. U.S.A., 95 (19), p. 11342–11347, 1998, ISSN: 0027-8424.

Résumé | BibTeX | Étiquettes: Bacteria, Chromatography, Cloning, Hemolymph, High Pressure Liquid, Immunity, Insect Proteins, Mass, Matrix-Assisted Laser Desorption-Ionization, Messenger, Molecular, Peptides, Protein Precursors, RNA, Sequence Analysis, Spectrometry, Time Factors


Levashina, Elena A; Ohresser, S; Lemaitre, Bruno; Imler, Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Article de journal

Journal of Molecular Biology, 278 (3), p. 515–527, 1998, ISSN: 0022-2836.

Résumé | Liens | BibTeX | Étiquettes: Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, Insect, Insect Proteins, Larva, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription


Articles de journaux


Richman, A M; Bulet, Philippe; Hetru, Charles; Barillas-Mury, Carolina; Hoffmann, Jules A; Kafalos, Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Article de journal

Insect Mol. Biol., 5 (3), p. 203–210, 1996, ISSN: 0962-1075.

Résumé | BibTeX | Étiquettes: Amino Acid, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, Insect, Insect Vectors, Larva, Micrococcus luteus, Molecular, Sequence Homology


Articles de journaux


Levashina, Elena A; Ohresser, S; Bulet, Philippe ; Reichhart, Jean-Marc ; Hetru, Charles ; Hoffmann, Jules A

Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties Article de journal

Eur. J. Biochem., 233 (2), p. 694–700, 1995, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Antifungal Agents, Antimicrobial Cationic Peptides, Bacteria, Base Sequence, Cells, Chromosome Mapping, Cloning, Cultured, Genetic, Molecular, Peptides, Proline, Transcription


Cornet, B; Bonmatin, J M; Hetru, Charles; Hoffmann, Jules A; Ptak, M; Vovelle, F

Refined three-dimensional solution structure of insect defensin A Article de journal

Structure, 3 (5), p. 435–448, 1995, ISSN: 0969-2126.

Résumé | BibTeX | Étiquettes: Amino Acid, Bacteriolysis, Chemistry, Defensins, Diptera, Gram-Positive Bacteria, Hydrogen Bonding, Insect Hormones, Magnetic Resonance Spectroscopy, Models, Molecular, Physical, Physicochemical Phenomena, Protein Conformation, Recombinant Proteins, Sequence Homology, Solutions, Structure-Activity Relationship


Articles de journaux


Fehlbaum, P; Bulet, Philippe; Michaut, L; Lagueux, Marie; Broekaert, W F; Hetru, Charles; Hoffmann, Jules A

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides Article de journal

J. Biol. Chem., 269 (52), p. 33159–33163, 1994, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Amino Acid, Antifungal Agents, Base Sequence, Cloning, Complementary, DNA, Insect Proteins, Male, Messenger, Microbial Sensitivity Tests, Molecular, Peptide Biosynthesis, Peptides, Plants, Protein Biosynthesis, Protein Precursors, Proteins, RNA, Sequence Homology


Dimarcq, Jean-Luc; Hoffmann, Danièle ; Meister, Marie ; Bulet, Philippe ; Lanot, R; Reichhart, Jean-Marc ; Hoffmann, Jules A

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity Article de journal

Eur. J. Biochem., 221 (1), p. 201–209, 1994, ISSN: 0014-2956.

Résumé | BibTeX | Étiquettes: Base Sequence, Blood Proteins, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Genetic, Gram-Positive Bacteria, Larva, Molecular, Molecular Structure, Nucleic Acid, Protein Precursors, Regulatory Sequences, Transcription


Articles de journaux


Bulet, Philippe; Dimarcq, Jean-Luc; Hetru, Charles; Lagueux, Marie; Charlet, Maurice; Hegy, G; Dorsselaer, Alan Van; Hoffmann, Jules A

A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution Article de journal

J. Biol. Chem., 268 (20), p. 14893–14897, 1993, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Base Sequence, Carbohydrates, Cloning, DNA, Escherichia coli, Gas Chromatography-Mass Spectrometry, Glycopeptides, Glycosylation, Molecular


Kappler, Christine; Meister, Marie ; Lagueux, Marie ; Gateff, E; Hoffmann, Jules A; Reichhart, Jean-Marc

Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila Article de journal

EMBO J., 12 (4), p. 1561–1568, 1993, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Insect, Insect Hormones, Insect Proteins, Lipopolysaccharides, Messenger, Molecular, NF-kappa B, Nucleic Acid, Oligodeoxyribonucleotides, Promoter Regions, Regulatory Sequences, RNA, Transfection


Articles de journaux


Bonmatin, J M; Bonnat, J L; Gallet, X; Vovelle, F; Ptak, M; Reichhart, Jean-Marc ; Hoffmann, Jules A; Keppi, E; Legrain, M; Achstetter, T

Two-dimensional 1H NMR study of recombinant insect defensin A in water: resonance assignments, secondary structure and global folding Article de journal

J. Biomol. NMR, 2 (3), p. 235–256, 1992, ISSN: 0925-2738.

Résumé | BibTeX | Étiquettes: Defensins, Hydrogen, Insect Hormones, Insects, Magnetic Resonance Spectroscopy, Models, Molecular, Protein Conformation, Recombinant Proteins, Saccharomyces cerevisiae, Thermodynamics


Articles de journaux


Dimarcq, Jean-Luc; Zachary, Daniel ; Hoffmann, Jules A; Hoffmann, Danièle ; Reichhart, Jean-Marc

Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae Article de journal

EMBO J., 9 (8), p. 2507–2515, 1990, ISSN: 0261-4189.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Base Sequence, Blood Proteins, Cloning, Defensins, Diptera, Gene Expression, Insect Hormones, Insect Proteins, Larva, Molecular, Nucleic Acid Hybridization, Oligonucleotide Probes, Protein Conformation


Wicker, C; Reichhart, Jean-Marc ; Hoffmann, Danièle ; Hultmark, D; Samakovlis, C; Hoffmann, Jules A

Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides Article de journal

J. Biol. Chem., 265 (36), p. 22493–22498, 1990, ISSN: 0021-9258.

Résumé | BibTeX | Étiquettes: Anti-Bacterial Agents, Base Sequence, Cloning, Diptera, DNA, Escherichia coli, Insect Hormones, Insect Proteins, Molecular, Multigene Family, Nucleic Acid, Oligonucleotide Probes, Sequence Homology