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2009

Journal Articles

33.

Shia, Alice K H; Glittenberg, Marcus; Thompson, Gavin; Weber, Alexander N R; Reichhart, Jean-Marc; Ligoxygakis, Petros

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes Journal Article

J. Cell. Sci., 122 (Pt 24), pp. 4505–4515, 2009, ISSN: 1477-9137.

Abstract | Links | BibTeX | Tags: Enterococcus faecalis, Escherichia coli, Fat Body, Hemocytes, Larva, Toll-Like Receptors

2006

Journal Articles

32.

Bischoff, Vincent; Vignal, Cécile; Duvic, Bernard; Boneca, Ivo G; Hoffmann, Jules A; Royet, Julien

Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2 Journal Article

PLoS Pathog., 2 (2), pp. e14, 2006, ISSN: 1553-7374.

Abstract | Links | BibTeX | Tags: Antimicrobial Cationic Peptides, Bacteria, Carrier Proteins, Down-Regulation, Larva, RNA Interference, Signal Transduction

2005

Journal Articles

31.

Irving, Phil; Ubeda, Jean-Michel; Doucet, Daniel; Troxler, Laurent; Lagueux, Marie; Zachary, Daniel; Hoffmann, Jules A; Hetru, Charles; Meister, Marie

New insights into Drosophila larval haemocyte functions through genome-wide analysis Journal Article

Cell. Microbiol., 7 (3), pp. 335–350, 2005, ISSN: 1462-5814.

Abstract | Links | BibTeX | Tags: bioinformatic, Catechol Oxidase, Cell Lineage, Enzyme Precursors, Escherichia coli, Fat Body, Gene Expression Profiling, Genome, Hemocytes, Integrin alpha Chains, Integrins, Larva, Micrococcus luteus

2002

Journal Articles

30.

Munier, Anne-Isabelle; Doucet, Daniel; Perrodou, Emmanuel; Zachary, Daniel; Meister, Marie; Hoffmann, Jules A; Janeway, Charles A; Lagueux, Marie

PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae Journal Article

EMBO Rep., 3 (12), pp. 1195–1200, 2002, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Antibodies, Blotting, Cell Differentiation, Hemocytes, Immunohistochemistry, Larva, Ligands, Platelet-Derived Growth Factor, Receptors, Vascular Endothelial Growth Factor, Western

29.

Kambris, Zakaria; Hoffmann, Jules A; Imler, Jean-Luc ; Capovilla, Maria

Tissue and stage-specific expression of the Tolls in Drosophila embryos Journal Article

Gene expression patterns: GEP, 2 (3-4), pp. 311–317, 2002, ISSN: 1567-133X.

Abstract | BibTeX | Tags: Blotting, Cell Surface, Gene Expression Profiling, Larva, Multigene Family, Northern, Receptors, Toll-Like Receptors

28.

Duvic, Bernard; Hoffmann, Jules A; Meister, Marie; Royet, Julien

Notch signaling controls lineage specification during Drosophila larval hematopoiesis Journal Article

Curr. Biol., 12 (22), pp. 1923–1927, 2002, ISSN: 0960-9822.

Abstract | BibTeX | Tags: Cell Differentiation, Hematopoiesis, Larva, Lymphoid Tissue, Membrane Proteins, Notch, Receptors, Signal Transduction

27.

Ligoxygakis, Petros; Bulet, Philippe; Reichhart, Jean-Marc

Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila Journal Article

EMBO Rep., 3 (7), pp. 666–673, 2002, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Cell Adhesion Molecules, Fat Body, Gene Expression Regulation, Genes, Immunohistochemistry, Immunologic, Insect, Insect Proteins, Larva, Mass, Matrix-Assisted Laser Desorption-Ionization, Membrane Proteins, Receptors, Reporter, Spectrometry, Transgenes

2000

Journal Articles

26.

Basset, A; Khush, R S; Braun, A; Gardan, L; Boccard, F; Hoffmann, Jules A; Lemaitre, Bruno

The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response Journal Article

Proc. Natl. Acad. Sci. U.S.A., 97 (7), pp. 3376–3381, 2000, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Bacterial, Gene Expression Regulation, Genetically Modified, Insect Proteins, Larva, Pectobacterium carotovorum

25.

Imler, Jean-Luc; Hoffmann, Jules A

Toll and Toll-like proteins: an ancient family of receptors signaling infection Journal Article

Reviews in Immunogenetics, 2 (3), pp. 294–304, 2000, ISSN: 1398-1714.

Abstract | BibTeX | Tags: Adaptor Proteins, Antigens, Autoantigens, CD14, Cell Adhesion Molecules, Cell Surface, Differentiation, DNA-Binding Proteins, Gene Expression Regulation, I-kappa B Proteins, Immunity, Immunologic, Infection, Innate, Insect Proteins, Interleukin-1 Receptor-Associated Kinases, Knockout, Larva, Lipopolysaccharides, Mammals, MAP Kinase Signaling System, Membrane Glycoproteins, Membrane Proteins, Mice, Multigene Family, Myeloid Differentiation Factor 88, NF-kappa B, Peptidoglycan, Phosphorylation, Post-Translational, Protein Kinases, Protein Processing, Protein Structure, Receptors, Recombinant Fusion Proteins, Signal Transducing, Signal Transduction, Teichoic Acids, Tertiary, Toll-Like Receptor 4, Toll-Like Receptor 5, Toll-Like Receptor 6, Toll-Like Receptor 9, Toll-Like Receptors, Ubiquitins

1999

Journal Articles

24.

Manfruelli, P; Reichhart, Jean-Marc ; Steward, R; Hoffmann, Jules A; Lemaitre, Bruno

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF Journal Article

EMBO J., 18 (12), pp. 3380–3391, 1999, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Anti-Infective Agents, Cell Surface, Clone Cells, DNA-Binding Proteins, Fat Body, Female, Gene Expression Regulation, Genes, Insect, Insect Proteins, Larva, Male, Membrane Glycoproteins, Mosaicism, Mutation, Nuclear Proteins, Phosphoproteins, Receptors, Reporter, Signal Transduction, Toll-Like Receptors, Transcription Factors

23.

Lamberty, M; Ades, S; Uttenweiler-Joseph, S; Brookhart, G; Bushey, D; Hoffmann, Jules A; Bulet, Philippe

Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity Journal Article

J. Biol. Chem., 274 (14), pp. 9320–9326, 1999, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Antifungal Agents, Capillary, Chromatography, Defensins, Electrophoresis, Escherichia coli, Hemolymph, High Pressure Liquid, Insect Proteins, Larva, Lepidoptera, Micrococcus luteus, Proteins, Sequence Homology

1998

Journal Articles

22.

Braun, A; Hoffmann, Jules A; Meister, Marie

Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes Journal Article

Proc. Natl. Acad. Sci. U.S.A., 95 (24), pp. 14337–14342, 1998, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Adipose Tissue, Candida, Escherichia coli, Fungal, Genotype, Hemocytes, Larva, Melanins, Micrococcus luteus, Spores

21.

Ferrandon, Dominique; Jung, Alain C; Criqui, M; Lemaitre, Bruno; Uttenweiler-Joseph, S; Michaut, Lydia; Reichhart, Jean-Marc; Hoffmann, Jules A

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway Journal Article

EMBO J., 17 (5), pp. 1217–1227, 1998, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Bacteria, Cell Surface, Developmental, Digestive System, Epithelium, Fat Body, Female, Fungal, Gene Expression Regulation, Genes, Green Fluorescent Proteins, Insect Proteins, Larva, Luminescent Proteins, Male, Membrane Glycoproteins, Organ Specificity, Receptors, Reporter, Respiratory System, Spores, Toll-Like Receptors, Trachea, Transgenes

20.

Nicolas, E; Reichhart, Jean-Marc ; Hoffmann, Jules A; Lemaitre, Bruno

In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila Journal Article

J. Biol. Chem., 273 (17), pp. 10463–10469, 1998, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Cell Surface, DNA-Binding Proteins, Gene Expression Regulation, Insect Proteins, Larva, Membrane Glycoproteins, Phosphoproteins, Proto-Oncogene Proteins, Receptors, Signal Transduction, Toll-Like Receptors, Transcription Factor RelB, Transcription Factors

19.

Levashina, Elena A; Ohresser, S; Lemaitre, Bruno; Imler, Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Journal Article

Journal of Molecular Biology, 278 (3), pp. 515–527, 1998, ISSN: 0022-2836.

Abstract | Links | BibTeX | Tags: Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, Insect, Insect Proteins, Larva, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1996

Journal Articles

18.

Richman, A M; Bulet, Philippe; Hetru, Charles; Barillas-Mury, Carolina; Hoffmann, Jules A; Kafalos, Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Journal Article

Insect Mol. Biol., 5 (3), pp. 203–210, 1996, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Amino Acid, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, Insect, Insect Vectors, Larva, Micrococcus luteus, Molecular, Sequence Homology

1995

Journal Articles

17.

Bulet, Philippe; Hegy, G; Lambert, J; van Dorsselaer, Alan; Hoffmann, Jules A; Hetru, Charles

Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity Journal Article

Biochemistry, 34 (22), pp. 7394–7400, 1995, ISSN: 0006-2960.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Carbohydrate Sequence, Carbohydrates, Diptera, Escherichia coli, Glycopeptides, Hemolymph, Insect Hormones, Insect Proteins, Larva, Mass Spectrometry, Plants, Trisaccharides

1994

Journal Articles

16.

Dimarcq, Jean-Luc; Hoffmann, Danièle ; Meister, Marie ; Bulet, Philippe ; Lanot, R; Reichhart, Jean-Marc ; Hoffmann, Jules A

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity Journal Article

Eur. J. Biochem., 221 (1), pp. 201–209, 1994, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Base Sequence, Blood Proteins, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Genetic, Gram-Positive Bacteria, Larva, Molecular, Molecular Structure, Nucleic Acid, Protein Precursors, Regulatory Sequences, Transcription

1993

Journal Articles

15.

Georgel, Philippe; Meister, Marie ; Kappler, Christine ; Lemaitre, Bruno ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements Journal Article

Biochem. Biophys. Res. Commun., 197 (2), pp. 508–517, 1993, ISSN: 0006-291X.

Abstract | Links | BibTeX | Tags: Acute-Phase Proteins, Anti-Infective Agents, Base Sequence, Cell Line, Deoxyribonuclease I, DNA-Binding Proteins, Genetic, Insect Hormones, Insect Proteins, Larva, Mammals, NF-kappa B, Nucleic Acid, Oligonucleotide Probes, Polymerase Chain Reaction, Promoter Regions, Regulatory Sequences

1992

Journal Articles

14.

Bulet, Philippe; Cociancich, S; Reuland, M; Sauber, F; Bischoff, R; Hegy, G; Dorsselaer, Van A; Hetru, Charles; Hoffmann, Jules A

A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata) Journal Article

Eur. J. Biochem., 209 (3), pp. 977–984, 1992, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Blood Bactericidal Activity, Blood Proteins, Defensins, Hemolymph, Insect Proteins, Insects, Larva, Mass Spectrometry, Peptides

1990

Journal Articles

13.

Dimarcq, Jean-Luc; Zachary, Daniel ; Hoffmann, Jules A; Hoffmann, Danièle ; Reichhart, Jean-Marc

Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae Journal Article

EMBO J., 9 (8), pp. 2507–2515, 1990, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Base Sequence, Blood Proteins, Cloning, Defensins, Diptera, Gene Expression, Insect Hormones, Insect Proteins, Larva, Molecular, Nucleic Acid Hybridization, Oligonucleotide Probes, Protein Conformation

1988

Journal Articles

12.

Dimarcq, Jean-Luc; Keppi, E; Dunbar, B; Lambert, J; Reichhart, Jean-Marc ; Hoffmann, Danièle ; Rankine, S M; Fothergill, J E; Hoffmann, Jules A

Insect immunity. Purification and characterization of a family of novel inducible antibacterial proteins from immunized larvae of the dipteran Phormia terranovae and complete amino-acid sequence of the predominant member, diptericin A Journal Article

Eur. J. Biochem., 171 (1-2), pp. 17–22, 1988, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Amino Acids, Anti-Bacterial Agents, Diptera, Escherichia coli, Insect Hormones, Insect Proteins, Isoelectric Point, Larva

1985

Journal Articles

11.

Meister, Marie F; Dimarcq, Jean-Luc; Kappler, Christine; Hetru, Charles; Lagueux, Marie; Lanot, R; Luu, B; Hoffmann, Jules A

Conversion of a radiolabelled ecdysone precursor, 2,22,25-trideoxyecdysone, by embryonic and larval tissues of Locusta migratoria Journal Article

Mol. Cell. Endocrinol., 41 (1), pp. 27–44, 1985, ISSN: 0303-7207.

Abstract | BibTeX | Tags: Abdomen, Cholestenones, Chromatography, Ecdysone, Epidermis, Fat Body, Grasshoppers, Head, High Pressure Liquid, Hydroxylation, Larva, Malpighian Tubules, Thorax

1980

Journal Articles

10.

Zachary, Daniel; Hoffmann, Jules A

Endocrine control of the metamorphosis of the larval muscles in Calliphora erythrocephala (Diptera): in vitro studies of the role of ecdysteroids Journal Article

Dev. Biol., 80 (1), pp. 235–247, 1980, ISSN: 0012-1606.

BibTeX | Tags: Biological, Diptera, Ecdysone, Ecdysterone, Larva, Metamorphosis, Muscles, Organ Culture Techniques

1977

Journal Articles

9.

Hoffmann, Danièle; Brehelin, M; Hoffmann, Jules A

First results of the antibacterial defense reactions of Locusta migratoria larva and imago Journal Article

Ann Parasitol Hum Comp, 52 (1), pp. 87–88, 1977, ISSN: 0003-4150.

BibTeX | Tags: Bacillus thuringiensis, Bacteria, Cellular, Grasshoppers, Hematopoietic System, Hemocytes, Hemolymph, Immunity, Larva, Muramidase

1976

Journal Articles

8.

Feyereisen, R; Lagueux, Marie; Hoffmann, Jules A

Dynamics of ecdysone metabolism after ingestion and injection in Locusta migratoria Journal Article

Gen. Comp. Endocrinol., 29 (3), pp. 319–327, 1976, ISSN: 0016-6480.

BibTeX | Tags: Ecdysone, Grasshoppers, Hydroxylation, Injections, Intestines, Larva, Malpighian Tubules, Oral

1975

Journal Articles

7.

Feyereisen, R; Lagueux, Marie; Hoffmann, Jules A

The hemolymphatic transport of molting hormone during the development of Locusta migratoria L Journal Article

C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., 280 (14), pp. 1709–1712, 1975.

Abstract | BibTeX | Tags: Age Factors, Carrier Proteins, Chromatography, Ecdysone, Ecdysterone, Gel, Grasshoppers, Hematopoietic System, Larva, Neurosecretory Systems, Protein Binding, Time Factors

6.

Hoffmann, Jules A; Koolman, J; Beyler, C

The role of the prothoracic glands in the production of ecdysone during the last larval instar of Locusta migratoria L Journal Article

C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., 280 (6), pp. 733–736, 1975.

Abstract | BibTeX | Tags: Cholesterol, Ecdysone, Grasshoppers, Larva

1974

Journal Articles

5.

Hoffmann, Jules A; Weins, M J

Active protein synthesis in the prothoracic glands and ecdysone titer in the permanent larvae of Locusta migratoria after selective irradiation of hematopoietic tissue Journal Article

Experientia, 30 (7), pp. 821–822, 1974, ISSN: 0014-4754.

BibTeX | Tags: Ecdysone, Grasshoppers, Hematopoietic System, Larva, Leucine, Protein Biosynthesis, Radiation Effects, Tritium

4.

Hoffmann, Jules A; Koolman, J; Karlson, P; Joly, P

Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria (Orthoptera) Journal Article

Gen. Comp. Endocrinol., 22 (1), pp. 90–97, 1974, ISSN: 0016-6480.

BibTeX | Tags: Age Factors, Chromatography, Ecdysone, Feces, Grasshoppers, Hydroxylation, Invertebrate Hormones, Larva, Thin Layer, Time Factors, Tritium

1973

Journal Articles

3.

Koolman, J; Hoffmann, Jules A; Karlson, P

Sulphage esters as inactivation products of ecdysone in Locusta migratoria Journal Article

Hoppe-Seyler's Z. Physiol. Chem., 354 (9), pp. 1043–1048, 1973, ISSN: 0018-4888.

BibTeX | Tags: Biological, Cattle, Chromatography, Ecdysone, Electrophoresis, Esterases, Glucosidases, Glucuronidase, Grasshoppers, Hydrogen-Ion Concentration, Hydrolysis, Ion Exchange, Isotope Labeling, Kinetics, Larva, Liver, Metamorphosis, Paper, Plants, Saccharomyces cerevisiae, Snails, Sulfatases, Sulfur Radioisotopes, Sulfuric Acids, Swine, Thin Layer, Time Factors, Tritium

2.

Zachary, Daniel; Hoffmann, Jules A

The haemocytes of Calliphora erythrocephala (Meig.) (Diptera) Journal Article

Z Zellforsch Mikrosk Anat, 141 (1), pp. 55–73, 1973, ISSN: 0340-0336.

BibTeX | Tags: Cell Count, Cell Nucleus, Diptera, Electron, Endoplasmic Reticulum, Hemolymph, Hemostasis, Inclusion Bodies, Larva, Lipids, Lysosomes, Microscopy, Mitochondria, Phase-Contrast, Pupa, Radiation Effects

1.

Joly, L; Weins, M J; Hoffmann, Jules A; Porte, A

Development of the prothoracic glands of permanent larvae of Locusta migratoria obtained by selective irradiation of the hemocytopoietic tissue Journal Article

Z Zellforsch Mikrosk Anat, 137 (3), pp. 387–397, 1973, ISSN: 0340-0336.

BibTeX | Tags: Age Factors, Biological, Ecdysone, Electron, Endocrine Glands, Golgi Apparatus, Grasshoppers, Larva, Metamorphosis, Microscopy, Radiation Effects, Ribosomes