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2011

Journal Articles

13.

Nehme, Nadine T; Quintin, Jessica; Cho, Ju Hyun; Lee, Janice; Lafarge, Marie-Céline; Kocks, Christine; Ferrandon, Dominique

Relative roles of the cellular and humoral responses in the Drosophila host defense against three gram-positive bacterial infections Journal Article

PLoS ONE, 6 (3), pp. e14743, 2011, ISSN: 1932-6203.

Abstract | Links | BibTeX | Tags: Antimicrobial Cationic Peptides, Carrier Proteins, Cell Surface, Cellular, Enterococcus faecalis, Gram-Positive Bacteria, Gram-Positive Bacterial Infections, Host-Pathogen Interactions, Humoral, Immunity, Innate, Micrococcus luteus, Opsonin Proteins, Phagocytosis, Receptors, Signal Transduction, Solubility, Staphylococcus aureus

2005

Journal Articles

12.

Irving, Phil; Ubeda, Jean-Michel; Doucet, Daniel; Troxler, Laurent; Lagueux, Marie; Zachary, Daniel; Hoffmann, Jules A; Hetru, Charles; Meister, Marie

New insights into Drosophila larval haemocyte functions through genome-wide analysis Journal Article

Cell. Microbiol., 7 (3), pp. 335–350, 2005, ISSN: 1462-5814.

Abstract | Links | BibTeX | Tags: bioinformatic, Catechol Oxidase, Cell Lineage, Enzyme Precursors, Escherichia coli, Fat Body, Gene Expression Profiling, Genome, Hemocytes, Integrin alpha Chains, Integrins, Larva, Micrococcus luteus

2002

Journal Articles

11.

Tauszig-Delamasure, Servane; Bilak, Hana ; Capovilla, Maria ; Hoffmann, Jules A; Imler, Jean-Luc

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Journal Article

Nature Immunology, 3 (1), pp. 91–97, 2002, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Amino Acid, Antigens, Antimicrobial Cationic Peptides, Cell Surface, Chromosome Mapping, Differentiation, Disease Susceptibility, Enterococcus faecalis, Epistasis, Escherichia coli, Female, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Gram-Negative Bacteria, Hypocreales, Immunologic, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Myeloid Differentiation Factor 88, Protein Structure, Protein-Serine-Threonine Kinases, Receptors, Recombinant Fusion Proteins, Sequence Alignment, Sequence Homology, Signal Transducing, Tertiary, Toll-Like Receptors, Transfection

2001

Journal Articles

10.

Michel, T; Reichhart, Jean-Marc ; Hoffmann, Jules A; Royet, Julien

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein Journal Article

Nature, 414 (6865), pp. 756–759, 2001, ISSN: 0028-0836.

Abstract | Links | BibTeX | Tags: Amino Acid, Anti-Bacterial Agents, Anti-Infective Agents, Bacillus thuringiensis, Carrier Proteins, Cell Surface, Chromosome Mapping, Enterococcus faecalis, Fungi, Genes, Gram-Positive Bacteria, Hemolymph, Humans, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Mutation, Receptors, Sequence Homology, Toll-Like Receptors

2000

Journal Articles

9.

Hetru, Charles; Letellier, L; Oren, Z; Hoffmann, Jules A; Shai, Y

Androctonin, a hydrophilic disulphide-bridged non-haemolytic anti-microbial peptide: a plausible mode of action Journal Article

Biochem. J., 345 Pt 3 , pp. 653–664, 2000, ISSN: 0264-6021.

Abstract | BibTeX | Tags: Adenosine Triphosphate, Anti-Bacterial Agents, Cations, Cell Membrane Permeability, Cytoplasm, Disulfides, Electron, Escherichia coli, Fluoresceins, Fluorescent Dyes, Fourier Transform Infrared, Gram-Negative Bacteria, Insect Proteins, Liposomes, Microbial Sensitivity Tests, Micrococcus luteus, Microscopy, Oxygen, Phospholipids, Potassium, Proteins, Spectroscopy

1999

Journal Articles

8.

Levashina, Elena A; Langley, E; Green, C; Gubb, David ; Ashburner, M; Hoffmann, Jules A; Reichhart, Jean-Marc

Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila Journal Article

Science, 285 (5435), pp. 1917–1919, 1999, ISSN: 0036-8075.

Abstract | BibTeX | Tags: Antifungal Agents, Antimicrobial Cationic Peptides, Body Patterning, Cell Surface, Escherichia coli, Genes, Hemolymph, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Mutagenesis, Peptides, Receptors, Recombinant Fusion Proteins, Serine Proteinase Inhibitors, Serpins, Signal Transduction, Toll-Like Receptors, Up-Regulation

7.

Lamberty, M; Ades, S; Uttenweiler-Joseph, S; Brookhart, G; Bushey, D; Hoffmann, Jules A; Bulet, Philippe

Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity Journal Article

J. Biol. Chem., 274 (14), pp. 9320–9326, 1999, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Antifungal Agents, Capillary, Chromatography, Defensins, Electrophoresis, Escherichia coli, Hemolymph, High Pressure Liquid, Insect Proteins, Larva, Lepidoptera, Micrococcus luteus, Proteins, Sequence Homology

6.

Lowenberger, C A; Kamal, S; Chiles, J; Paskewitz, S; Bulet, Philippe; Hoffmann, Jules A; Christensen, B M

Mosquito-Plasmodium interactions in response to immune activation of the vector Journal Article

Exp. Parasitol., 91 (1), pp. 59–69, 1999, ISSN: 0014-4894.

Abstract | Links | BibTeX | Tags: Aedes, Anopheles, Culicidae, Defensins, Digestive System, Escherichia coli, Female, Genetic, Hemolymph, Insect Vectors, Messenger, Micrococcus luteus, Plasmodium, Plasmodium berghei, Plasmodium gallinaceum, Proteins, Reverse Transcriptase Polymerase Chain Reaction, RNA, Transcription

1998

Journal Articles

5.

Braun, A; Hoffmann, Jules A; Meister, Marie

Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes Journal Article

Proc. Natl. Acad. Sci. U.S.A., 95 (24), pp. 14337–14342, 1998, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Adipose Tissue, Candida, Escherichia coli, Fungal, Genotype, Hemocytes, Larva, Melanins, Micrococcus luteus, Spores

1996

Journal Articles

4.

Richman, A M; Bulet, Philippe; Hetru, Charles; Barillas-Mury, Carolina; Hoffmann, Jules A; Kafalos, Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Journal Article

Insect Mol. Biol., 5 (3), pp. 203–210, 1996, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Amino Acid, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, Insect, Insect Vectors, Larva, Micrococcus luteus, Molecular, Sequence Homology

3.

Lowenberger, C A; Ferdig, M T; Bulet, Philippe; Khalili, S; Hoffmann, Jules A; Christensen, B M

Aedes aegypti: induced antibacterial proteins reduce the establishment and development of Brugia malayi Journal Article

Exp. Parasitol., 83 (2), pp. 191–201, 1996, ISSN: 0014-4894.

Abstract | Links | BibTeX | Tags: Aedes, Analysis of Variance, Anti-Bacterial Agents, Base Sequence, Blood Proteins, Blotting, Brugia malayi, Culicidae, Defensins, DNA, Escherichia coli, Fat Body, Genetic, Gerbillinae, Micrococcus luteus, Microfilaria, Northern, RNA, Transcription

1995

Journal Articles

2.

Lowenberger, C; Bulet, Philippe; Charlet, Maurice; Hetru, Charles; Hodgeman, B; Christensen, B M; Hoffmann, Jules A

Insect immunity: isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti Journal Article

Insect Biochem. Mol. Biol., 25 (7), pp. 867–873, 1995, ISSN: 0965-1748.

Abstract | BibTeX | Tags: Aedes, Amino Acid, Anti-Bacterial Agents, Blood Proteins, Defensins, Escherichia coli, Gram-Negative Bacteria, Gram-Positive Bacteria, Immunity, Insect Vectors, Micrococcus luteus, Sequence Homology, Stereoisomerism

1993

Journal Articles

1.

Cociancich, S; Ghazi, A; Hetru, Charles; Hoffmann, Jules A; Letellier, L

Insect defensin, an inducible antibacterial peptide, forms voltage-dependent channels in Micrococcus luteus Journal Article

J. Biol. Chem., 268 (26), pp. 19239–19245, 1993, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Adenosine Triphosphate, Anti-Bacterial Agents, Blood Proteins, Cell Membrane, Cytoplasm, Defensins, Hydrogen-Ion Concentration, Insects, Ion Channels, Kinetics, Membrane Potentials, Micrococcus luteus, Osmolar Concentration, Oxygen Consumption, Potassium, Recombinant Proteins, Temperature