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2006

Journal Articles

8.

Leclerc, Vincent; Pelte, Nadège ; Chamy, Laure El ; Martinelli, Cosimo ; Ligoxygakis, Petros ; Hoffmann, Jules A; Reichhart, Jean-Marc

Prophenoloxidase activation is not required for survival to microbial infections in Drosophila Journal Article

EMBO Rep., 7 (2), pp. 231–235, 2006, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Bacterial Infections, Catechol Oxidase, Enzyme Activation, Enzyme Precursors, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, Immunity, Innate, Mutation, Survival Rate

2005

Journal Articles

7.

Kocks, Christine; Cho, Ju Hyun ; Nehme, Nadine ; Ulvila, Johanna ; Pearson, Alan M; Meister, Marie ; Strom, Charles ; Conto, Stephanie L; Hetru, Charles ; Stuart, Lynda M; Stehle, Thilo ; Hoffmann, Jules A; Reichhart, Jean-Marc ; Ferrandon, Dominique ; Rämet, Mika ; Ezekowitz, Alan R B

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila Journal Article

Cell, 123 (2), pp. 335–346, 2005, ISSN: 0092-8674.

Abstract | Links | BibTeX | Tags: Amino Acid, Amino Acid Motifs, Bacterial Infections, Cell Surface, Embryo, Escherichia coli, Flow Cytometry, Frameshift Mutation, Genes, Histidine, In Situ Hybridization, Insect, Insect Proteins, Macrophages, Membrane Proteins, Messenger, Nonmammalian, Open Reading Frames, Phagocytosis, Receptors, RNA, RNA Interference, Sequence Homology, Serratia marcescens

6.

Royet, Julien; Reichhart, Jean-Marc ; Hoffmann, Jules A

Sensing and signaling during infection in Drosophila Journal Article

Curr. Opin. Immunol., 17 (1), pp. 11–17, 2005, ISSN: 0952-7915.

Abstract | Links | BibTeX | Tags: Antimicrobial Cationic Peptides, Bacterial Infections, Gene Expression Regulation, Genome, Immunity, Innate, Signal Transduction

2003

Journal Articles

5.

Hetru, Charles; Troxler, Laurent; Hoffmann, Jules A

Drosophila melanogaster antimicrobial defense Journal Article

J. Infect. Dis., 187 Suppl 2 , pp. S327–334, 2003, ISSN: 0022-1899.

Abstract | Links | BibTeX | Tags: Animal, Bacterial Infections, bioinformatic, Immunity, Innate, Mycoses, Parasitic Diseases, Peptides, Signal Transduction

2001

Journal Articles

4.

Georgel, Philippe; Naitza, S; Kappler, Christine ; Ferrandon, Dominique ; Zachary, Daniel ; Swimmer, C; Kopczynski, C; Duyk, G; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis Journal Article

Dev. Cell, 1 (4), pp. 503–514, 2001, ISSN: 1534-5807.

Abstract | BibTeX | Tags: Anti-Infective Agents, Apoptosis, Bacterial Infections, Caspases, Chromosome Mapping, Cysteine Proteinase Inhibitors, DNA Damage, Female, Gene Expression, I-kappa B Kinase, Immunocompromised Host, In Situ Nick-End Labeling, Insect Proteins, Male, Mutation, Phenotype, Protein Structure, Protein-Serine-Threonine Kinases, Tertiary

1997

Journal Articles

3.

Dimarcq, Jean-Luc; Imler, Jean-Luc ; Lanot, R; Ezekowitz, Alan R B; Hoffmann, Jules A; Janeway, C A; Lagueux, Marie

Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression Journal Article

Insect Biochemistry and Molecular Biology, 27 (10), pp. 877–886, 1997, ISSN: 0965-1748.

Abstract | BibTeX | Tags: Bacterial Infections, Cellular, Ecdysone, Gene Expression, Genes, Hemocytes, Hemolymph, Immunity, Insect, Macrophages, Peptide Biosynthesis, Phagocytosis

1995

Journal Articles

2.

Lemaitre, Bruno; Kromer-Metzger, E; Michaut, Lydia ; Nicolas, E; Meister, Marie ; Georgel, Philippe ; Reichhart, Jean-Marc ; Hoffmann, Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

Proc. Natl. Acad. Sci. U.S.A., 92 (21), pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, Insect, Insect Hormones, Insect Proteins, Male, Mutation, Mycoses, Nucleic Acid, Peptides, Protein Binding, Recessive, Regulatory Sequences, Reporter, Survival Analysis

1992

Journal Articles

1.

Hoffmann, Jules A; Hetru, Charles

Insect defensins: inducible antibacterial peptides Journal Article

Immunol. Today, 13 (10), pp. 411–415, 1992, ISSN: 0167-5699.

Abstract | Links | BibTeX | Tags: Amino Acid, Bacterial Infections, Blood Bactericidal Activity, Blood Proteins, Defensins, Insects, Peptides, Sequence Homology