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2002

Journal Articles

8.

Ligoxygakis, Petros; Pelte, Nadège ; Hoffmann, Jules A; Reichhart, Jean-Marc

Activation of Drosophila Toll during fungal infection by a blood serine protease Journal Article

Science, 297 (5578), pp. 114–116, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Cell Surface, Chromosome Mapping, Escherichia coli, Female, Gene Expression Regulation, Genes, Gram-Positive Cocci, Hemolymph, Hypocreales, Insect, Insect Proteins, Male, Mutation, Protein Sorting Signals, Protein Structure, Receptors, Serine Endopeptidases, Tertiary, Toll-Like Receptors

7.

Tauszig-Delamasure, Servane; Bilak, Hana ; Capovilla, Maria ; Hoffmann, Jules A; Imler, Jean-Luc

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Journal Article

Nature Immunology, 3 (1), pp. 91–97, 2002, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Amino Acid, Antigens, Antimicrobial Cationic Peptides, Cell Surface, Chromosome Mapping, Differentiation, Disease Susceptibility, Enterococcus faecalis, Epistasis, Escherichia coli, Female, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Gram-Negative Bacteria, Hypocreales, Immunologic, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Myeloid Differentiation Factor 88, Protein Structure, Protein-Serine-Threonine Kinases, Receptors, Recombinant Fusion Proteins, Sequence Alignment, Sequence Homology, Signal Transducing, Tertiary, Toll-Like Receptors, Transfection

2001

Journal Articles

6.

Michel, T; Reichhart, Jean-Marc ; Hoffmann, Jules A; Royet, Julien

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein Journal Article

Nature, 414 (6865), pp. 756–759, 2001, ISSN: 0028-0836.

Abstract | Links | BibTeX | Tags: Amino Acid, Anti-Bacterial Agents, Anti-Infective Agents, Bacillus thuringiensis, Carrier Proteins, Cell Surface, Chromosome Mapping, Enterococcus faecalis, Fungi, Genes, Gram-Positive Bacteria, Hemolymph, Humans, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Mutation, Receptors, Sequence Homology, Toll-Like Receptors

5.

Vizioli, J; Bulet, Philippe; Hoffmann, Jules A; Kafatos, Fotis C; Müller, H M; Dimopoulos, G

Gambicin: a novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae Journal Article

Proc. Natl. Acad. Sci. U.S.A., 98 (22), pp. 12630–12635, 2001, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Anopheles, Anti-Bacterial Agents, Anti-Infective Agents, Base Sequence, Chromosome Mapping, Insect Proteins, Insect Vectors, Malaria, Messenger, RNA

4.

Georgel, Philippe; Naitza, S; Kappler, Christine ; Ferrandon, Dominique ; Zachary, Daniel ; Swimmer, C; Kopczynski, C; Duyk, G; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis Journal Article

Dev. Cell, 1 (4), pp. 503–514, 2001, ISSN: 1534-5807.

Abstract | BibTeX | Tags: Anti-Infective Agents, Apoptosis, Bacterial Infections, Caspases, Chromosome Mapping, Cysteine Proteinase Inhibitors, DNA Damage, Female, Gene Expression, I-kappa B Kinase, Immunocompromised Host, In Situ Nick-End Labeling, Insect Proteins, Male, Mutation, Phenotype, Protein Structure, Protein-Serine-Threonine Kinases, Tertiary

1999

Journal Articles

3.

Lowenberger, C A; Smartt, C T; Bulet, Philippe; Ferdig, M T; Severson, D W; Hoffmann, Jules A; Christensen, B M

Insect immunity: molecular cloning, expression, and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti Journal Article

Insect Mol. Biol., 8 (1), pp. 107–118, 1999, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Aedes, Amino Acid, Base Sequence, Blotting, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Hemolymph, Molecular, Northern, Protein Isoforms, Proteins, Sequence Homology

1995

Journal Articles

2.

Levashina, Elena A; Ohresser, S; Bulet, Philippe ; Reichhart, Jean-Marc ; Hetru, Charles ; Hoffmann, Jules A

Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties Journal Article

Eur. J. Biochem., 233 (2), pp. 694–700, 1995, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Antifungal Agents, Antimicrobial Cationic Peptides, Bacteria, Base Sequence, Cells, Chromosome Mapping, Cloning, Cultured, Genetic, Molecular, Peptides, Proline, Transcription

1994

Journal Articles

1.

Dimarcq, Jean-Luc; Hoffmann, Danièle ; Meister, Marie ; Bulet, Philippe ; Lanot, R; Reichhart, Jean-Marc ; Hoffmann, Jules A

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity Journal Article

Eur. J. Biochem., 221 (1), pp. 201–209, 1994, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Base Sequence, Blood Proteins, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Genetic, Gram-Positive Bacteria, Larva, Molecular, Molecular Structure, Nucleic Acid, Protein Precursors, Regulatory Sequences, Transcription