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2014

Journal Articles

15.

Bonnay, François; Nguyen, Xuan-Hung; Cohen-Berros, Eva; Troxler, Laurent; Batsche, Eric; Camonis, Jacques; Takeuchi, Osamu; Reichhart, Jean-Marc; Matt, Nicolas

Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling Journal Article

EMBO J., 33 (20), pp. 2349–2362, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: bioinformatic, Cell Cycle Proteins, Chromatin Assembly and Disassembly, chromatin remodeling, DNA-Binding Proteins, Female, Genetic, Immunity, Innate, Innate immune response, Male, Mutation, NF-kappa B, NF‐κB, Promoter Regions, Proteomics, Trans-Activators, Transcription Factors, Transcriptional Activation, Two-Hybrid System Techniques

14.

Goto, Akira; Fukuyama, Hidehiro ; Imler, Jean-Luc ; Hoffmann, Jules A

The chromatin regulator DMAP1 modulates activity of the nuclear factor B (NF-B) transcription factor Relish in the Drosophila innate immune response Journal Article

The Journal of Biological Chemistry, 289 (30), pp. 20470–20476, 2014, ISSN: 1083-351X.

Abstract | Links | BibTeX | Tags: Cell Line, Chromatin Assembly and Disassembly, Epistasis, Escherichia coli, Escherichia coli Infections, Genetic, Immunity, Innate, NF-kappa B, Repressor Proteins, Signal Transduction, Transcription Factors

2011

Journal Articles

13.

Lee, Kwang-Zin; Ferrandon, Dominique

Negative regulation of immune responses on the fly Journal Article

EMBO J., 30 (6), pp. 988–990, 2011, ISSN: 1460-2075.

Links | BibTeX | Tags: *Gene Expression Regulation, *Homeostasis, Bacteria, Bacteria/*immunology, Biological, Drosophila melanogaster/*immunology, Drosophila Proteins/biosynthesis/metabolism, Gene Expression Regulation, Homeostasis, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Kinases/metabolism, Models, NF-kappa B, NF-kappa B/metabolism, ras Proteins, ras Proteins/metabolism, Receptor Protein-Tyrosine Kinases, Receptor Protein-Tyrosine Kinases/metabolism

2010

Journal Articles

12.

Paquette, Nicholas; Broemer, Meike; Aggarwal, Kamna; Chen, Li; Husson, Marie; Ertürk-Hasdemir, Deniz; Reichhart, Jean-Marc; Meier, Pascal; Silverman, Neal

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling Journal Article

Mol. Cell, 37 (2), pp. 172–182, 2010, ISSN: 1097-4164.

Abstract | Links | BibTeX | Tags: Alleles, Amino Acid Motifs, Biological, Caspases, Inhibitor of Apoptosis Proteins, MAP Kinase Kinase Kinases, Models, NF-kappa B, Sequence Alignment, Signal Transduction, Ubiquitin-Protein Ligases, Ubiquitination

2009

Journal Articles

11.

Hetru, Charles; Hoffmann, Jules A

NF-kappaB in the immune response of Drosophila Journal Article

Cold Spring Harb Perspect Biol, 1 (6), pp. a000232, 2009, ISSN: 1943-0264.

Abstract | Links | BibTeX | Tags: Bacteria, Fungi, Gene Expression Regulation, NF-kappa B

2008

Journal Articles

10.

Goto, Akira; Matsushita, Kazufumi ; Gesellchen, Viola ; Chamy, Laure El ; Kuttenkeuler, David ; Takeuchi, Osamu ; Hoffmann, Jules A; Akira, Shizuo ; Boutros, Michael ; Reichhart, Jean-Marc

Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice Journal Article

Nat. Immunol., 9 (1), pp. 97–104, 2008, ISSN: 1529-2916.

Abstract | Links | BibTeX | Tags: Cell Line, Embryo, Fibroblasts, Humans, Immunity, Innate, Interleukin-1beta, Mammalian, Mice, NF-kappa B, Nuclear Proteins, Proteins, Signal Transduction, Toll-Like Receptors, Transgenic, Tumor Necrosis Factor-alpha

2006

Journal Articles

9.

Frolet, Cécile; Thoma, Martine; Blandin, Stéphanie A; Hoffmann, Jules A; Levashina, Elena A

Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei Journal Article

Immunity, 25 (4), pp. 677–685, 2006, ISSN: 1074-7613.

Abstract | Links | BibTeX | Tags: Anopheles gambiae, Gene Expression, Gene Expression Regulation, Genes, Immunity, Insect, NF-kappa B, Plasmodium berghei, Telomerase

2000

Journal Articles

8.

Imler, Jean-Luc; Hoffmann, Jules A

Toll and Toll-like proteins: an ancient family of receptors signaling infection Journal Article

Reviews in Immunogenetics, 2 (3), pp. 294–304, 2000, ISSN: 1398-1714.

Abstract | BibTeX | Tags: Adaptor Proteins, Antigens, Autoantigens, CD14, Cell Adhesion Molecules, Cell Surface, Differentiation, DNA-Binding Proteins, Gene Expression Regulation, I-kappa B Proteins, Immunity, Immunologic, Infection, Innate, Insect Proteins, Interleukin-1 Receptor-Associated Kinases, Knockout, Larva, Lipopolysaccharides, Mammals, MAP Kinase Signaling System, Membrane Glycoproteins, Membrane Proteins, Mice, Multigene Family, Myeloid Differentiation Factor 88, NF-kappa B, Peptidoglycan, Phosphorylation, Post-Translational, Protein Kinases, Protein Processing, Protein Structure, Receptors, Recombinant Fusion Proteins, Signal Transducing, Signal Transduction, Teichoic Acids, Tertiary, Toll-Like Receptor 4, Toll-Like Receptor 5, Toll-Like Receptor 6, Toll-Like Receptor 9, Toll-Like Receptors, Ubiquitins

1996

Journal Articles

7.

Barillas-Mury, Carolina; Charlesworth, A; Gross, I; Richman, A; Hoffmann, Jules A; Kafatos, Fotis C

Immune factor Gambif1, a new rel family member from the human malaria vector, Anopheles gambiae Journal Article

EMBO J., 15 (17), pp. 4691–4701, 1996, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Amino Acid, Anopheles, Base Sequence, Biological Transport, Cell Nucleus, Cells, Complementary, Cultured, DNA, DNA-Binding Proteins, Insect Proteins, Insect Vectors, NF-kappa B, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-rel, Sequence Homology, Trans-Activators, Transcriptional Activation

6.

Gross, I; Georgel, Philippe ; Kappler, Christine ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immunity: a comparative analysis of the Rel proteins dorsal and Dif in the induction of the genes encoding diptericin and cecropin Journal Article

Nucleic Acids Res., 24 (7), pp. 1238–1245, 1996, ISSN: 0305-1048.

Abstract | BibTeX | Tags: Antimicrobial Cationic Peptides, Base Sequence, DNA Primers, DNA-Binding Proteins, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, NF-kappa B, Nuclear Proteins, Peptides, Phosphoproteins, Transcription, Transcription Factors, Transcriptional Activation

5.

Lemaitre, Bruno; Nicolas, E; Michaut, Lydia ; Reichhart, Jean-Marc ; Hoffmann, Jules A

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults Journal Article

Cell, 86 (6), pp. 973–983, 1996, ISSN: 0092-8674.

Abstract | BibTeX | Tags: Antifungal Agents, Cell Surface, DNA-Binding Proteins, Fungi, Gene Expression, Genes, Insect, Insect Hormones, Insect Proteins, Membrane Glycoproteins, MHC Class II, Mutation, Mycoses, NF-kappa B, Phosphoproteins, Proteins, Receptors, Signal Transduction, Toll-Like Receptors

1995

Journal Articles

4.

Georgel, Philippe; Kappler, Christine ; Langley, E; Gross, I; Nicolas, E; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immunity. A sequence homologous to mammalian interferon consensus response element enhances the activity of the diptericin promoter Journal Article

Nucleic Acids Res., 23 (7), pp. 1140–1145, 1995, ISSN: 0305-1048.

Abstract | BibTeX | Tags: Base Sequence, CCAAT-Enhancer-Binding Proteins, DNA, DNA-Binding Proteins, Genes, Genetic, Immunity, Insect, Insect Hormones, Insect Proteins, Interferons, Lipopolysaccharides, NF-kappa B, Nuclear Proteins, Plasmids, Promoter Regions, Up-Regulation

1993

Journal Articles

3.

Georgel, Philippe; Meister, Marie ; Kappler, Christine ; Lemaitre, Bruno ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements Journal Article

Biochem. Biophys. Res. Commun., 197 (2), pp. 508–517, 1993, ISSN: 0006-291X.

Abstract | Links | BibTeX | Tags: Acute-Phase Proteins, Anti-Infective Agents, Base Sequence, Cell Line, Deoxyribonuclease I, DNA-Binding Proteins, Genetic, Insect Hormones, Insect Proteins, Larva, Mammals, NF-kappa B, Nucleic Acid, Oligonucleotide Probes, Polymerase Chain Reaction, Promoter Regions, Regulatory Sequences

2.

Kappler, Christine; Meister, Marie ; Lagueux, Marie ; Gateff, E; Hoffmann, Jules A; Reichhart, Jean-Marc

Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila Journal Article

EMBO J., 12 (4), pp. 1561–1568, 1993, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Insect, Insect Hormones, Insect Proteins, Lipopolysaccharides, Messenger, Molecular, NF-kappa B, Nucleic Acid, Oligodeoxyribonucleotides, Promoter Regions, Regulatory Sequences, RNA, Transfection

1.

Reichhart, Jean-Marc; Georgel, Philippe ; Meister, Marie ; Lemaitre, Bruno ; Kappler, Christine ; Hoffmann, Jules A

Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila Journal Article

C. R. Acad. Sci. III, Sci. Vie, 316 (10), pp. 1218–1224, 1993, ISSN: 0764-4469.

Abstract | BibTeX | Tags: Blotting, Cellular, Gene Expression, Genes, Genetic, Immunity, Insect, NF-kappa B, Northern, Translocation, Zygote