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2015

Journal Articles

10.

Paro, Simona; Imler, Jean-Luc; Meignin, Carine

Sensing viral RNAs by Dicer/RIG-I like ATPases across species Journal Article

Current Opinion in Immunology, 32 , pp. 106–113, 2015, ISSN: 1879-0372.

Abstract | Links | BibTeX | Tags: Adenosine Triphosphatases, DEAD-box RNA Helicases, Humans, Protein Binding, Protein Interaction Domains and Motifs, Ribonuclease III, RNA, Viral, Virus Diseases, Viruses

2014

Journal Articles

9.

Tartey, Sarang; Matsushita, Kazufumi ; Vandenbon, Alexis ; Ori, Daisuke ; Imamura, Tomoko ; Mino, Takashi ; Standley, Daron M; Hoffmann, Jules A; Reichhart, Jean-Marc ; Akira, Shizuo ; Takeuchi, Osamu

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex Journal Article

EMBO J., 33 (20), pp. 2332–2348, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Cell Nucleus, Chromatin Assembly and Disassembly, chromatin remodeling, Chromosomal Proteins, cytokine, Cytokines, Female, Gene Expression Regulation, gene regulation, Genetic, Humans, Immunity, Innate, innate immunity, Knockout, Listeria monocytogenes, Macrophages, Male, Mice, Multiprotein Complexes, Non-Histone, Nuclear Proteins, Promoter Regions, Protein Binding, Repressor Proteins, Sequence Deletion, Signal Transducing, Transcriptional Activation

2013

Journal Articles

8.

Kobayashi, Taira; Ogawa, Michinaga; Sanada, Takahito; Mimuro, Hitomi; Kim, Minsoo; Ashida, Hiroshi; Akakura, Reiko; Yoshida, Mitsutaka; Kawalec, Magdalena; Reichhart, Jean-Marc; Mizushima, Tsunehiro; Sasakawa, Chihiro

The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection Journal Article

Cell Host Microbe, 13 (5), pp. 570–583, 2013, ISSN: 1934-6069.

Abstract | Links | BibTeX | Tags: Animal, Bacillary, Bacterial, Bacterial Proteins, Caspases, Cell Death, Cell Line, Disease Models, DNA, Dysentery, Enzyme Inhibitors, Epithelial Cells, Escherichia coli, Gene Knockout Techniques, Guinea Pigs, Host-Pathogen Interactions, Humans, Initiator, Protein Binding, Protein Interaction Mapping, Salmonella typhimurium, Sequence Analysis, Shigella flexneri, Virulence Factors

2010

Journal Articles

7.

Whisstock, James C; Silverman, Gary A; Bird, Phillip I; Bottomley, Stephen P; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Huntington, James A

Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions Journal Article

J. Biol. Chem., 285 (32), pp. 24307–24312, 2010, ISSN: 1083-351X.

Abstract | Links | BibTeX | Tags: Biological, Biological Transport, Biophysics, Catalytic Domain, Hormones, Humans, Kinetics, Models, Peptide Hydrolases, Protein Binding, Protein Conformation, Protein Structure, Serpins, Substrate Specificity, Tertiary, Thrombin

2009

Journal Articles

6.

Fraiture, Malou; Baxter, Richard H G; Steinert, Stefanie; Chelliah, Yogarany; Frolet, Cécile; Quispe-Tintaya, Wilber; Hoffmann, Jules A; Blandin, Stéphanie A; Levashina, Elena A

Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium Journal Article

Cell Host Microbe, 5 (3), pp. 273–284, 2009, ISSN: 1934-6069.

Abstract | Links | BibTeX | Tags: Anopheles, APL1, Biological, Complement System Proteins, Hemolymph, Immunologic Factors, LRIM1, Models, Plasmodium, Protein Binding, Proteins, TEP1

2007

Journal Articles

5.

Weber, Alexander N R; Gangloff, Monique; Moncrieffe, Martin C; Hyvert, Yann; Imler, Jean-Luc; Gay, Nicholas J

Role of the Spatzle Pro-domain in the generation of an active toll receptor ligand Journal Article

The Journal of Biological Chemistry, 282 (18), pp. 13522–13531, 2007, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Cytokines, Dimerization, Ligands, Post-Translational, Protein Binding, Protein Processing, Protein Structure, Signal Transduction, Tertiary, Toll-Like Receptors

2005

Journal Articles

4.

Weber, Alexander N R; Moncrieffe, Martin C; Gangloff, Monique; Imler, Jean-Luc; Gay, Nicholas J

Ligand-receptor and receptor-receptor interactions act in concert to activate signaling in the Drosophila toll pathway Journal Article

The Journal of Biological Chemistry, 280 (24), pp. 22793–22799, 2005, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Amino Acid, Biophysical Phenomena, Biophysics, Body Patterning, Calorimetry, Cell Line, Cell Surface, Cross-Linking Reagents, Cytokines, Dimerization, Electrophoresis, Humans, Ligands, Luciferases, Membrane Glycoproteins, Polyacrylamide Gel, Protein Binding, Protein Structure, Receptors, Recombinant Proteins, Sequence Homology, Signal Transduction, Tertiary, Time Factors, Toll-Like Receptors, Ultracentrifugation

2003

Journal Articles

3.

Weber, Alexander N R; Tauszig-Delamasure, Servane ; Hoffmann, Jules A; Lelièvre, Eric ; Gascan, Hugues ; Ray, Keith P; Morse, Mary A; Imler, Jean-Luc ; Gay, Nicholas J

Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling Journal Article

Nature Immunology, 4 (8), pp. 794–800, 2003, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Cell Surface, Insect Proteins, Protein Binding, Protein Structure, Receptors, Signal Transduction, Tertiary, Toll-Like Receptors

1995

Journal Articles

2.

Lemaitre, Bruno; Kromer-Metzger, E; Michaut, Lydia ; Nicolas, E; Meister, Marie ; Georgel, Philippe ; Reichhart, Jean-Marc ; Hoffmann, Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

Proc. Natl. Acad. Sci. U.S.A., 92 (21), pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, Insect, Insect Hormones, Insect Proteins, Male, Mutation, Mycoses, Nucleic Acid, Peptides, Protein Binding, Recessive, Regulatory Sequences, Reporter, Survival Analysis

1975

Journal Articles

1.

Feyereisen, R; Lagueux, Marie; Hoffmann, Jules A

The hemolymphatic transport of molting hormone during the development of Locusta migratoria L Journal Article

C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat., 280 (14), pp. 1709–1712, 1975.

Abstract | BibTeX | Tags: Age Factors, Carrier Proteins, Chromatography, Ecdysone, Ecdysterone, Gel, Grasshoppers, Hematopoietic System, Larva, Neurosecretory Systems, Protein Binding, Time Factors