Show all

2009

Journal Articles

11.

Fraiture, Malou; Baxter, Richard H G; Steinert, Stefanie; Chelliah, Yogarany; Frolet, Cécile; Quispe-Tintaya, Wilber; Hoffmann, Jules A; Blandin, Stéphanie A; Levashina, Elena A

Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium Journal Article

Cell Host Microbe, 5 (3), pp. 273–284, 2009, ISSN: 1934-6069.

Abstract | Links | BibTeX | Tags: Anopheles, APL1, Biological, Complement System Proteins, Hemolymph, Immunologic Factors, LRIM1, Models, Plasmodium, Protein Binding, Proteins, TEP1

2008

Journal Articles

10.

Goto, Akira; Matsushita, Kazufumi ; Gesellchen, Viola ; Chamy, Laure El ; Kuttenkeuler, David ; Takeuchi, Osamu ; Hoffmann, Jules A; Akira, Shizuo ; Boutros, Michael ; Reichhart, Jean-Marc

Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice Journal Article

Nat. Immunol., 9 (1), pp. 97–104, 2008, ISSN: 1529-2916.

Abstract | Links | BibTeX | Tags: Cell Line, Embryo, Fibroblasts, Humans, Immunity, Innate, Interleukin-1beta, Mammalian, Mice, NF-kappa B, Nuclear Proteins, Proteins, Signal Transduction, Toll-Like Receptors, Transgenic, Tumor Necrosis Factor-alpha

2000

Journal Articles

9.

Lagueux, Marie; Perrodou, E; Levashina, Elena A; Capovilla, Maria; Hoffmann, Jules A

Constitutive expression of a complement-like protein in toll and JAK gain-of-function mutants of Drosophila Journal Article

Proc. Natl. Acad. Sci. U.S.A., 97 (21), pp. 11427–11432, 2000, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: alpha-Macroglobulins, Amino Acid, Cell Surface, Complement C3, Esters, Genetic, Insect Proteins, Janus Kinases, Membrane Glycoproteins, Mutation, Protein-Tyrosine Kinases, Proteins, Receptors, Sequence Homology, Sulfhydryl Compounds, Toll-Like Receptors, Transcription, Transcription Factors

8.

Hetru, Charles; Letellier, L; Oren, Z; Hoffmann, Jules A; Shai, Y

Androctonin, a hydrophilic disulphide-bridged non-haemolytic anti-microbial peptide: a plausible mode of action Journal Article

Biochem. J., 345 Pt 3 , pp. 653–664, 2000, ISSN: 0264-6021.

Abstract | BibTeX | Tags: Adenosine Triphosphate, Anti-Bacterial Agents, Cations, Cell Membrane Permeability, Cytoplasm, Disulfides, Electron, Escherichia coli, Fluoresceins, Fluorescent Dyes, Fourier Transform Infrared, Gram-Negative Bacteria, Insect Proteins, Liposomes, Microbial Sensitivity Tests, Micrococcus luteus, Microscopy, Oxygen, Phospholipids, Potassium, Proteins, Spectroscopy

1999

Journal Articles

7.

Hoffmann, Jules A; Kafatos, Fotis C; Janeway, Charles A; Ezekowitz, Alan R B

Phylogenetic perspectives in innate immunity Journal Article

Science, 284 (5418), pp. 1313–1318, 1999, ISSN: 0036-8075.

Abstract | BibTeX | Tags: Active, Culicidae, Humans, Immunity, Immunological, Infection, Innate, Insect Vectors, Mammals, Models, Phagocytosis, Phylogeny, Proteins

6.

Lamberty, M; Ades, S; Uttenweiler-Joseph, S; Brookhart, G; Bushey, D; Hoffmann, Jules A; Bulet, Philippe

Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity Journal Article

J. Biol. Chem., 274 (14), pp. 9320–9326, 1999, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Antifungal Agents, Capillary, Chromatography, Defensins, Electrophoresis, Escherichia coli, Hemolymph, High Pressure Liquid, Insect Proteins, Larva, Lepidoptera, Micrococcus luteus, Proteins, Sequence Homology

5.

Lowenberger, C A; Smartt, C T; Bulet, Philippe; Ferdig, M T; Severson, D W; Hoffmann, Jules A; Christensen, B M

Insect immunity: molecular cloning, expression, and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti Journal Article

Insect Mol. Biol., 8 (1), pp. 107–118, 1999, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Aedes, Amino Acid, Base Sequence, Blotting, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Hemolymph, Molecular, Northern, Protein Isoforms, Proteins, Sequence Homology

4.

Lowenberger, C A; Kamal, S; Chiles, J; Paskewitz, S; Bulet, Philippe; Hoffmann, Jules A; Christensen, B M

Mosquito-Plasmodium interactions in response to immune activation of the vector Journal Article

Exp. Parasitol., 91 (1), pp. 59–69, 1999, ISSN: 0014-4894.

Abstract | Links | BibTeX | Tags: Aedes, Anopheles, Culicidae, Defensins, Digestive System, Escherichia coli, Female, Genetic, Hemolymph, Insect Vectors, Messenger, Micrococcus luteus, Plasmodium, Plasmodium berghei, Plasmodium gallinaceum, Proteins, Reverse Transcriptase Polymerase Chain Reaction, RNA, Transcription

1996

Journal Articles

3.

Lemaitre, Bruno; Nicolas, E; Michaut, Lydia ; Reichhart, Jean-Marc ; Hoffmann, Jules A

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults Journal Article

Cell, 86 (6), pp. 973–983, 1996, ISSN: 0092-8674.

Abstract | BibTeX | Tags: Antifungal Agents, Cell Surface, DNA-Binding Proteins, Fungi, Gene Expression, Genes, Insect, Insect Hormones, Insect Proteins, Membrane Glycoproteins, MHC Class II, Mutation, Mycoses, NF-kappa B, Phosphoproteins, Proteins, Receptors, Signal Transduction, Toll-Like Receptors

1994

Journal Articles

2.

Fehlbaum, P; Bulet, Philippe; Michaut, L; Lagueux, Marie; Broekaert, W F; Hetru, Charles; Hoffmann, Jules A

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides Journal Article

J. Biol. Chem., 269 (52), pp. 33159–33163, 1994, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Antifungal Agents, Base Sequence, Cloning, Complementary, DNA, Insect Proteins, Male, Messenger, Microbial Sensitivity Tests, Molecular, Peptide Biosynthesis, Peptides, Plants, Protein Biosynthesis, Protein Precursors, Proteins, RNA, Sequence Homology

1990

Journal Articles

1.

Hoffmann, Jules A; Hoffmann, Danièle

The inducible antibacterial peptides of dipteran insects Journal Article

Res. Immunol., 141 (9), pp. 910–918, 1990, ISSN: 0923-2494.

BibTeX | Tags: Antimicrobial Cationic Peptides, Defensins, Diptera, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, Nucleic Acid, Proteins, Sequence Homology, Transcription