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1996

Journal Articles

22.

Gross, I; Georgel, Philippe ; Kappler, Christine ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immunity: a comparative analysis of the Rel proteins dorsal and Dif in the induction of the genes encoding diptericin and cecropin Journal Article

Nucleic Acids Res., 24 (7), pp. 1238–1245, 1996, ISSN: 0305-1048.

Abstract | BibTeX | Tags: Antimicrobial Cationic Peptides, Base Sequence, DNA Primers, DNA-Binding Proteins, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, NF-kappa B, Nuclear Proteins, Peptides, Phosphoproteins, Transcription, Transcription Factors, Transcriptional Activation

21.

Lemaitre, Bruno; Nicolas, E; Michaut, Lydia ; Reichhart, Jean-Marc ; Hoffmann, Jules A

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults Journal Article

Cell, 86 (6), pp. 973–983, 1996, ISSN: 0092-8674.

Abstract | BibTeX | Tags: Antifungal Agents, Cell Surface, DNA-Binding Proteins, Fungi, Gene Expression, Genes, Insect, Insect Hormones, Insect Proteins, Membrane Glycoproteins, MHC Class II, Mutation, Mycoses, NF-kappa B, Phosphoproteins, Proteins, Receptors, Signal Transduction, Toll-Like Receptors

1995

Journal Articles

20.

Lemaitre, Bruno; Kromer-Metzger, E; Michaut, Lydia ; Nicolas, E; Meister, Marie ; Georgel, Philippe ; Reichhart, Jean-Marc ; Hoffmann, Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

Proc. Natl. Acad. Sci. U.S.A., 92 (21), pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, Insect, Insect Hormones, Insect Proteins, Male, Mutation, Mycoses, Nucleic Acid, Peptides, Protein Binding, Recessive, Regulatory Sequences, Reporter, Survival Analysis

19.

Bulet, Philippe; Hegy, G; Lambert, J; van Dorsselaer, Alan; Hoffmann, Jules A; Hetru, Charles

Insect immunity. The inducible antibacterial peptide diptericin carries two O-glycans necessary for biological activity Journal Article

Biochemistry, 34 (22), pp. 7394–7400, 1995, ISSN: 0006-2960.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Carbohydrate Sequence, Carbohydrates, Diptera, Escherichia coli, Glycopeptides, Hemolymph, Insect Hormones, Insect Proteins, Larva, Mass Spectrometry, Plants, Trisaccharides

18.

Cornet, B; Bonmatin, J M; Hetru, Charles; Hoffmann, Jules A; Ptak, M; Vovelle, F

Refined three-dimensional solution structure of insect defensin A Journal Article

Structure, 3 (5), pp. 435–448, 1995, ISSN: 0969-2126.

Abstract | BibTeX | Tags: Amino Acid, Bacteriolysis, Chemistry, Defensins, Diptera, Gram-Positive Bacteria, Hydrogen Bonding, Insect Hormones, Magnetic Resonance Spectroscopy, Models, Molecular, Physical, Physicochemical Phenomena, Protein Conformation, Recombinant Proteins, Sequence Homology, Solutions, Structure-Activity Relationship

17.

Georgel, Philippe; Kappler, Christine ; Langley, E; Gross, I; Nicolas, E; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immunity. A sequence homologous to mammalian interferon consensus response element enhances the activity of the diptericin promoter Journal Article

Nucleic Acids Res., 23 (7), pp. 1140–1145, 1995, ISSN: 0305-1048.

Abstract | BibTeX | Tags: Base Sequence, CCAAT-Enhancer-Binding Proteins, DNA, DNA-Binding Proteins, Genes, Genetic, Immunity, Insect, Insect Hormones, Insect Proteins, Interferons, Lipopolysaccharides, NF-kappa B, Nuclear Proteins, Plasmids, Promoter Regions, Up-Regulation

16.

Lemaitre, Bruno; Meister, Marie ; Govind, S; Georgel, Philippe ; Steward, R; Reichhart, Jean-Marc ; Hoffmann, Jules A

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila Journal Article

EMBO J., 14 (3), pp. 536–545, 1995, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Biological Transport, Cell Nucleus, Cell Surface, DNA-Binding Proteins, Fat Body, Gene Expression Regulation, Genetic, Immunity, Immunohistochemistry, Insect Hormones, Insect Proteins, Melanins, Membrane Glycoproteins, Mutation, Neoplasms, Nuclear Proteins, Phosphoproteins, Receptors, Signal Transduction, Toll-Like Receptors, Transcription, Transcription Factors

1994

Journal Articles

15.

Meister, Marie; Braun, A; Kappler, Christine ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter Journal Article

EMBO J., 13 (24), pp. 5958–5966, 1994, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Infective Agents, Base Sequence, beta-Galactosidase, DNA Mutational Analysis, Female, Gene Expression Regulation, Genetic, Genetically Modified, Germ Cells, Insect Hormones, Insect Proteins, Male, Models, Nucleic Acid, Promoter Regions, Recombinant Fusion Proteins, Repetitive Sequences, Transformation

14.

Ferrandon, Dominique; Elphick, L; Nüsslein-Volhard, C; Johnston, St D

Staufen protein associates with the 3'UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner Journal Article

Cell, 79 (7), pp. 1221–1232, 1994, ISSN: 0092-8674.

Abstract | BibTeX | Tags: Base Sequence, Cell Polarity, Homeodomain Proteins, Insect Hormones, Messenger, Microtubules, Nucleic Acid Conformation, Oocytes, RNA, RNA-Binding Proteins, Trans-Activators

1993

Journal Articles

13.

Georgel, Philippe; Meister, Marie ; Kappler, Christine ; Lemaitre, Bruno ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements Journal Article

Biochem. Biophys. Res. Commun., 197 (2), pp. 508–517, 1993, ISSN: 0006-291X.

Abstract | Links | BibTeX | Tags: Acute-Phase Proteins, Anti-Infective Agents, Base Sequence, Cell Line, Deoxyribonuclease I, DNA-Binding Proteins, Genetic, Insect Hormones, Insect Proteins, Larva, Mammals, NF-kappa B, Nucleic Acid, Oligonucleotide Probes, Polymerase Chain Reaction, Promoter Regions, Regulatory Sequences

12.

Hoffmann, Jules A; Hetru, Charles ; Reichhart, Jean-Marc

The humoral antibacterial response of Drosophila Journal Article

FEBS Lett., 325 (1-2), pp. 63–66, 1993, ISSN: 0014-5793.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Base Sequence, Genes, Insect, Insect Hormones, Insect Proteins, Sequence Homology

11.

Kappler, Christine; Meister, Marie ; Lagueux, Marie ; Gateff, E; Hoffmann, Jules A; Reichhart, Jean-Marc

Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila Journal Article

EMBO J., 12 (4), pp. 1561–1568, 1993, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Insect, Insect Hormones, Insect Proteins, Lipopolysaccharides, Messenger, Molecular, NF-kappa B, Nucleic Acid, Oligodeoxyribonucleotides, Promoter Regions, Regulatory Sequences, RNA, Transfection

1992

Journal Articles

10.

Bonmatin, J M; Bonnat, J L; Gallet, X; Vovelle, F; Ptak, M; Reichhart, Jean-Marc ; Hoffmann, Jules A; Keppi, E; Legrain, M; Achstetter, T

Two-dimensional 1H NMR study of recombinant insect defensin A in water: resonance assignments, secondary structure and global folding Journal Article

J. Biomol. NMR, 2 (3), pp. 235–256, 1992, ISSN: 0925-2738.

Abstract | BibTeX | Tags: Defensins, Hydrogen, Insect Hormones, Insects, Magnetic Resonance Spectroscopy, Models, Molecular, Protein Conformation, Recombinant Proteins, Saccharomyces cerevisiae, Thermodynamics

9.

Reichhart, Jean-Marc; Meister, Marie ; Dimarcq, Jean-Luc ; Zachary, Daniel ; Hoffmann, Danièle ; Ruiz, C; Richards, G; Hoffmann, Jules A

Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter Journal Article

EMBO J., 11 (4), pp. 1469–1477, 1992, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Acute-Phase Proteins, Adipose Tissue, Base Sequence, beta-Galactosidase, Embryo, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, Mammals, Nonmammalian, Oligodeoxyribonucleotides, Promoter Regions, Recombinant Fusion Proteins, Restriction Mapping

1991

Journal Articles

8.

Bulet, Philippe; Cociancich, S; Dimarcq, Jean-Luc ; Lambert, J; Reichhart, Jean-Marc ; Hoffmann, Danièle ; Hetru, Charles ; Hoffmann, Jules A

Insect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family Journal Article

J. Biol. Chem., 266 (36), pp. 24520–24525, 1991, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Antibody Formation, Beetles, Blood Bactericidal Activity, Blood Proteins, Chromatography, Defensins, Hemolymph, High Pressure Liquid, Insect Hormones, Insect Proteins

7.

Hetru, Charles; Li, K W; Bulet, Philippe; Lagueux, Marie; Hoffmann, Jules A

Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta migratoria Journal Article

Eur. J. Biochem., 201 (2), pp. 495–499, 1991, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Chromatography, DNA, Female, Grasshoppers, High Pressure Liquid, Insect Hormones, Insulin, Mass Spectrometry, Neuropeptides, Proinsulin, Protein Conformation

1990

Journal Articles

6.

Hoffmann, Jules A; Hoffmann, Danièle

The inducible antibacterial peptides of dipteran insects Journal Article

Res. Immunol., 141 (9), pp. 910–918, 1990, ISSN: 0923-2494.

BibTeX | Tags: Antimicrobial Cationic Peptides, Defensins, Diptera, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, Nucleic Acid, Proteins, Sequence Homology, Transcription

5.

Dimarcq, Jean-Luc; Zachary, Daniel ; Hoffmann, Jules A; Hoffmann, Danièle ; Reichhart, Jean-Marc

Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae Journal Article

EMBO J., 9 (8), pp. 2507–2515, 1990, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Base Sequence, Blood Proteins, Cloning, Defensins, Diptera, Gene Expression, Insect Hormones, Insect Proteins, Larva, Molecular, Nucleic Acid Hybridization, Oligonucleotide Probes, Protein Conformation

4.

Wicker, C; Reichhart, Jean-Marc ; Hoffmann, Danièle ; Hultmark, D; Samakovlis, C; Hoffmann, Jules A

Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides Journal Article

J. Biol. Chem., 265 (36), pp. 22493–22498, 1990, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Base Sequence, Cloning, Diptera, DNA, Escherichia coli, Insect Hormones, Insect Proteins, Molecular, Multigene Family, Nucleic Acid, Oligonucleotide Probes, Sequence Homology

1989

Journal Articles

3.

Reichhart, Jean-Marc; Essrich, M; Dimarcq, Jean-Luc ; Hoffmann, Danièle ; Hoffmann, Jules A; Lagueux, Marie

Insect immunity. Isolation of cDNA clones corresponding to diptericin, an inducible antibacterial peptide from Phormia terranovae (Diptera). Transcriptional profiles during immunization Journal Article

Eur. J. Biochem., 182 (2), pp. 423–427, 1989, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Bacterial Proteins, Base Sequence, Blotting, Diptera, DNA, Endoribonucleases, Enterobacter, Enterobacteriaceae, Gene Expression Regulation, Genes, Genetic, Insect Hormones, Insect Proteins, Messenger, MHC Class II, Northern, Ribonuclease H, RNA, Transcription

1988

Journal Articles

2.

Dimarcq, Jean-Luc; Keppi, E; Dunbar, B; Lambert, J; Reichhart, Jean-Marc ; Hoffmann, Danièle ; Rankine, S M; Fothergill, J E; Hoffmann, Jules A

Insect immunity. Purification and characterization of a family of novel inducible antibacterial proteins from immunized larvae of the dipteran Phormia terranovae and complete amino-acid sequence of the predominant member, diptericin A Journal Article

Eur. J. Biochem., 171 (1-2), pp. 17–22, 1988, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Amino Acids, Anti-Bacterial Agents, Diptera, Escherichia coli, Insect Hormones, Insect Proteins, Isoelectric Point, Larva

1985

Journal Articles

1.

Hetru, Charles; Luu, B; Hoffmann, Jules A

Ecdysone conjugates: isolation and identification Journal Article

Meth. Enzymol., 111 , pp. 411–419, 1985, ISSN: 0076-6879.

BibTeX | Tags: Bombyx, Chromatography, Ecdysone, Helix (Snails), High Pressure Liquid, Insect Hormones, Magnetic Resonance Spectroscopy, Mass Spectrometry, Spectrophotometry, Structure-Activity Relationship