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2006

Journal Articles

11.

Frolet, Cécile; Thoma, Martine; Blandin, Stéphanie A; Hoffmann, Jules A; Levashina, Elena A

Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei Journal Article

Immunity, 25 (4), pp. 677–685, 2006, ISSN: 1074-7613.

Abstract | Links | BibTeX | Tags: Anopheles gambiae, Gene Expression, Gene Expression Regulation, Genes, Immunity, Insect, NF-kappa B, Plasmodium berghei, Telomerase

2003

Journal Articles

10.

Gobert, Vanessa; Gottar, Marie; Matskevich, Alexey A; Rutschmann, Sophie; Royet, Julien; Belvin, Marcia; Hoffmann, Jules A; Ferrandon, Dominique

Dual activation of the Drosophila toll pathway by two pattern recognition receptors Journal Article

Science, 302 (5653), pp. 2126–2130, 2003, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Carrier Proteins, Cell Surface, DNA Transposable Elements, Gene Expression, Genes, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemolymph, Hypocreales, Insect, Insect Proteins, Mutation, Phenotype, Receptors, Serine Endopeptidases, Toll-Like Receptors

2001

Journal Articles

9.

Georgel, Philippe; Naitza, S; Kappler, Christine ; Ferrandon, Dominique ; Zachary, Daniel ; Swimmer, C; Kopczynski, C; Duyk, G; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis Journal Article

Dev. Cell, 1 (4), pp. 503–514, 2001, ISSN: 1534-5807.

Abstract | BibTeX | Tags: Anti-Infective Agents, Apoptosis, Bacterial Infections, Caspases, Chromosome Mapping, Cysteine Proteinase Inhibitors, DNA Damage, Female, Gene Expression, I-kappa B Kinase, Immunocompromised Host, In Situ Nick-End Labeling, Insect Proteins, Male, Mutation, Phenotype, Protein Structure, Protein-Serine-Threonine Kinases, Tertiary

8.

Boulanger, Nathalie; Ehret-Sabatier, Laurence; Brun, R; Zachary, Daniel; Bulet, Philippe; Imler, Jean-Luc

Immune response of Drosophila melanogaster to infection with the flagellate parasite Crithidia spp Journal Article

Insect Biochemistry and Molecular Biology, 31 (2), pp. 129–137, 2001, ISSN: 0965-1748.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Crithidia, Defensins, Gene Expression, Glycopeptides, Hemocytes, Insect Proteins, Phagocytosis

1999

Journal Articles

7.

Lowenberger, C A; Smartt, C T; Bulet, Philippe; Ferdig, M T; Severson, D W; Hoffmann, Jules A; Christensen, B M

Insect immunity: molecular cloning, expression, and characterization of cDNAs and genomic DNA encoding three isoforms of insect defensin in Aedes aegypti Journal Article

Insect Mol. Biol., 8 (1), pp. 107–118, 1999, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Aedes, Amino Acid, Base Sequence, Blotting, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Hemolymph, Molecular, Northern, Protein Isoforms, Proteins, Sequence Homology

1997

Journal Articles

6.

Dimarcq, Jean-Luc; Imler, Jean-Luc ; Lanot, R; Ezekowitz, Alan R B; Hoffmann, Jules A; Janeway, C A; Lagueux, Marie

Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression Journal Article

Insect Biochemistry and Molecular Biology, 27 (10), pp. 877–886, 1997, ISSN: 0965-1748.

Abstract | BibTeX | Tags: Bacterial Infections, Cellular, Ecdysone, Gene Expression, Genes, Hemocytes, Hemolymph, Immunity, Insect, Macrophages, Peptide Biosynthesis, Phagocytosis

1996

Journal Articles

5.

Richman, A M; Bulet, Philippe; Hetru, Charles; Barillas-Mury, Carolina; Hoffmann, Jules A; Kafalos, Fotis C

Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA Journal Article

Insect Mol. Biol., 5 (3), pp. 203–210, 1996, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Amino Acid, Anopheles, Base Sequence, Blood Bactericidal Activity, Blood Proteins, Cloning, Complementary, Defensins, DNA, Escherichia coli, Female, Gene Expression, Genes, Insect, Insect Vectors, Larva, Micrococcus luteus, Molecular, Sequence Homology

4.

Lemaitre, Bruno; Nicolas, E; Michaut, Lydia ; Reichhart, Jean-Marc ; Hoffmann, Jules A

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults Journal Article

Cell, 86 (6), pp. 973–983, 1996, ISSN: 0092-8674.

Abstract | BibTeX | Tags: Antifungal Agents, Cell Surface, DNA-Binding Proteins, Fungi, Gene Expression, Genes, Insect, Insect Hormones, Insect Proteins, Membrane Glycoproteins, MHC Class II, Mutation, Mycoses, NF-kappa B, Phosphoproteins, Proteins, Receptors, Signal Transduction, Toll-Like Receptors

1994

Journal Articles

3.

Dimarcq, Jean-Luc; Hoffmann, Danièle ; Meister, Marie ; Bulet, Philippe ; Lanot, R; Reichhart, Jean-Marc ; Hoffmann, Jules A

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity Journal Article

Eur. J. Biochem., 221 (1), pp. 201–209, 1994, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Base Sequence, Blood Proteins, Chromosome Mapping, Cloning, Complementary, Defensins, DNA, Gene Expression, Genetic, Gram-Positive Bacteria, Larva, Molecular, Molecular Structure, Nucleic Acid, Protein Precursors, Regulatory Sequences, Transcription

1993

Journal Articles

2.

Reichhart, Jean-Marc; Georgel, Philippe ; Meister, Marie ; Lemaitre, Bruno ; Kappler, Christine ; Hoffmann, Jules A

Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila Journal Article

C. R. Acad. Sci. III, Sci. Vie, 316 (10), pp. 1218–1224, 1993, ISSN: 0764-4469.

Abstract | BibTeX | Tags: Blotting, Cellular, Gene Expression, Genes, Genetic, Immunity, Insect, NF-kappa B, Northern, Translocation, Zygote

1990

Journal Articles

1.

Dimarcq, Jean-Luc; Zachary, Daniel ; Hoffmann, Jules A; Hoffmann, Danièle ; Reichhart, Jean-Marc

Insect immunity: expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae Journal Article

EMBO J., 9 (8), pp. 2507–2515, 1990, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Base Sequence, Blood Proteins, Cloning, Defensins, Diptera, Gene Expression, Insect Hormones, Insect Proteins, Larva, Molecular, Nucleic Acid Hybridization, Oligonucleotide Probes, Protein Conformation