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2017

Journal Articles

10.

Patrnogic, Jelena; Leclerc, Vincent

The serine protease homolog spheroide is involved in sensing of pathogenic Gram-positive bacteria Journal Article

PLoS One, 12 (12), 2017.

Abstract | Links | BibTeX | Tags: Fungi, Gram-Positive Bacteria, serine protease, spheroide, toll pathway

2011

Journal Articles

9.

Limmer, Stefanie; Quintin, Jessica; Hetru, Charles; Ferrandon, Dominique

Virulence on the fly: Drosophila melanogaster as a model genetic organism to decipher host-pathogen interactions Journal Article

Curr Drug Targets, 12 (7), pp. 978–999, 2011, ISSN: 1873-5592.

Abstract | BibTeX | Tags: Animal, Anti-Infective Agents, Disease Models, Drug Delivery Systems, Drug Design, Drug Resistance, Fungi, High-Throughput Screening Assays, Host-Pathogen Interactions, Humans, Microbial, Pseudomonas aeruginosa

2010

Journal Articles

8.

Matskevich, Alexey A; Quintin, Jessica; Ferrandon, Dominique

The Drosophila PRR GNBP3 assembles effector complexes involved in antifungal defenses independently of its Toll-pathway activation function Journal Article

Eur. J. Immunol., 40 (5), pp. 1244–1254, 2010, ISSN: 1521-4141.

Abstract | Links | BibTeX | Tags: Agglutination, Beauveria, Beauveria/immunology, Candida albicans, Candida albicans/immunology, Carrier Proteins, Carrier Proteins/*immunology/pharmacology, Drosophila melanogaster/*immunology/microbiology, Drosophila Proteins/*immunology/pharmacology/physiology, Enzyme Activation, Fungal, Fungi, Fungi/*immunology, Hemolymph, Hemolymph/immunology, Melanins, Melanins/*physiology, Monophenol Monooxygenase, Monophenol Monooxygenase/physiology, Multiprotein Complexes, Multiprotein Complexes/physiology, Recombinant Fusion Proteins, Recombinant Fusion Proteins/pharmacology, Serpins, Serpins/physiology, Spores, Toll-Like Receptors, Toll-Like Receptors/immunology

2009

Journal Articles

7.

Hetru, Charles; Hoffmann, Jules A

NF-kappaB in the immune response of Drosophila Journal Article

Cold Spring Harb Perspect Biol, 1 (6), pp. a000232, 2009, ISSN: 1943-0264.

Abstract | Links | BibTeX | Tags: Bacteria, Fungi, Gene Expression Regulation, NF-kappa B

2008

Journal Articles

6.

Chamy, Laure El; Leclerc, Vincent; Caldelari, Isabelle; Reichhart, Jean-Marc

Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll Journal Article

Nat. Immunol., 9 (10), pp. 1165–1170, 2008, ISSN: 1529-2916.

Abstract | Links | BibTeX | Tags: Fungi, Genetically Modified, Gram-Positive Bacteria, Gram-Positive Bacterial Infections, In Situ Hybridization, Mycoses, Pattern Recognition, Peptide Hydrolases, Receptors, Serine Endopeptidases, Signal Transduction, Toll-Like Receptors

2003

Journal Articles

5.

Thouzeau, Cécile; Maho, Yvon Le; Froget, Guillaume; Sabatier, Laurence; Bohec, Céline Le; Hoffmann, Jules A; Bulet, Philippe

Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus Journal Article

J. Biol. Chem., 278 (51), pp. 51053–51058, 2003, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Antimicrobial Cationic Peptides, Bacteria, beta-Defensins, Birds, Feeding Behavior, Fungi, Gastrointestinal Contents, Male, Mass, Matrix-Assisted Laser Desorption-Ionization, Protein Isoforms, Sequence Alignment, Spectrometry

4.

Bilak, Hana; Tauszig-Delamasure, S; Imler, Jean-Luc

Toll and Toll-like receptors in Drosophila Journal Article

Biochemical Society Transactions, 31 (Pt 3), pp. 648–651, 2003, ISSN: 0300-5127.

Abstract | Links | BibTeX | Tags: Biological Evolution, Cell Surface, Fungi, Genome, Gram-Negative Bacteria, Gram-Positive Bacteria, Membrane Glycoproteins, Receptors, Toll-Like Receptor 5, Toll-Like Receptors

2001

Journal Articles

3.

Michel, T; Reichhart, Jean-Marc ; Hoffmann, Jules A; Royet, Julien

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein Journal Article

Nature, 414 (6865), pp. 756–759, 2001, ISSN: 0028-0836.

Abstract | Links | BibTeX | Tags: Amino Acid, Anti-Bacterial Agents, Anti-Infective Agents, Bacillus thuringiensis, Carrier Proteins, Cell Surface, Chromosome Mapping, Enterococcus faecalis, Fungi, Genes, Gram-Positive Bacteria, Hemolymph, Humans, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Mutation, Receptors, Sequence Homology, Toll-Like Receptors

1996

Journal Articles

2.

Fehlbaum, P; Bulet, Philippe; Chernysh, S; Briand, J P; Roussel, J P; Letellier, L; Hetru, Charles; Hoffmann, Jules A

Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides Journal Article

Proc. Natl. Acad. Sci. U.S.A., 93 (3), pp. 1221–1225, 1996, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Amino Acid, Amphibian Proteins, Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Cyclic, Fungi, Gram-Negative Bacteria, Gram-Positive Bacteria, Hemiptera, Mass Spectrometry, Microbial Sensitivity Tests, Peptides, Ranidae, Sequence Homology, Skin, Structure-Activity Relationship

1.

Lemaitre, Bruno; Nicolas, E; Michaut, Lydia ; Reichhart, Jean-Marc ; Hoffmann, Jules A

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults Journal Article

Cell, 86 (6), pp. 973–983, 1996, ISSN: 0092-8674.

Abstract | BibTeX | Tags: Antifungal Agents, Cell Surface, DNA-Binding Proteins, Fungi, Gene Expression, Genes, Insect, Insect Hormones, Insect Proteins, Membrane Glycoproteins, MHC Class II, Mutation, Mycoses, NF-kappa B, Phosphoproteins, Proteins, Receptors, Signal Transduction, Toll-Like Receptors