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2014

Journal Articles

42.

Tartey, Sarang; Matsushita, Kazufumi ; Vandenbon, Alexis ; Ori, Daisuke ; Imamura, Tomoko ; Mino, Takashi ; Standley, Daron M; Hoffmann, Jules A; Reichhart, Jean-Marc ; Akira, Shizuo ; Takeuchi, Osamu

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex Journal Article

EMBO J., 33 (20), pp. 2332–2348, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Cell Nucleus, Chromatin Assembly and Disassembly, chromatin remodeling, Chromosomal Proteins, cytokine, Cytokines, Female, Gene Expression Regulation, gene regulation, Genetic, Humans, Immunity, Innate, innate immunity, Knockout, Listeria monocytogenes, Macrophages, Male, Mice, Multiprotein Complexes, Non-Histone, Nuclear Proteins, Promoter Regions, Protein Binding, Repressor Proteins, Sequence Deletion, Signal Transducing, Transcriptional Activation

41.

Lamiable, Olivier; Imler, Jean-Luc

Induced antiviral innate immunity in Drosophila Journal Article

Current Opinion in Microbiology, 20 , pp. 62–68, 2014, ISSN: 1879-0364.

Abstract | Links | BibTeX | Tags: Gene Expression Regulation, Host-Pathogen Interactions, Immunity, Innate, RNA Viruses, Signal Transduction

2013

Journal Articles

40.

Kemp, Cordula; Mueller, Stefanie ; Goto, Akira ; Barbier, Vincent ; Paro, Simona ; Bonnay, François ; Dostert, Catherine ; Troxler, Laurent ; Hetru, Charles ; Meignin, Carine ; Pfeffer, Sébastien ; Hoffmann, Jules A; Imler, Jean-Luc

Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila Journal Article

Journal of Immunology (Baltimore, Md.: 1950), 190 (2), pp. 650–658, 2013, ISSN: 1550-6606.

Abstract | Links | BibTeX | Tags: Alphavirus, Alphavirus Infections, bioinformatic, DNA Virus Infections, Gene Expression Regulation, Genetically Modified, Janus Kinases, Male, Nodaviridae, Ribonuclease III, RNA Helicases, RNA Interference, RNA Virus Infections, Transcription Factors

2012

Journal Articles

39.

Lemaitre, Bruno; Nicolas, Emmanuelle ; Michaut, Lydia ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983 Journal Article

J. Immunol., 188 (11), pp. 5210–5220, 2012, ISSN: 1550-6606.

Abstract | BibTeX | Tags: Antifungal Agents, Developmental, DNA-Binding Proteins, Gene Expression Regulation, History, Multigene Family, Mycoses, Phosphoproteins, Toll-Like Receptors

38.

Deleury, Emeline; Dubreuil, Géraldine; Elangovan, Namasivayam; Wajnberg, Eric; Reichhart, Jean-Marc; Gourbal, Benjamin; Duval, David; Baron, Olga Lucia; Gouzy, Jérôme; Coustau, Christine

Specific versus non-specific immune responses in an invertebrate species evidenced by a comparative de novo sequencing study Journal Article

PLoS ONE, 7 (3), pp. e32512, 2012, ISSN: 1932-6203.

Abstract | Links | BibTeX | Tags: Biomphalaria, Calmodulin, Cluster Analysis, Complementary, DNA, Expressed Sequence Tags, Ferritins, Gene Expression Profiling, Gene Expression Regulation, High-Throughput Nucleotide Sequencing, Immunity, Innate, Messenger, Pattern Recognition, Phylogeny, Receptors, RNA, Signal Transduction, Zinc Fingers

2011

Journal Articles

37.

Aoun, Richard Bou; Hetru, Charles; Troxler, Laurent; Doucet, Daniel; Ferrandon, Dominique; Matt, Nicolas

Analysis of thioester-containing proteins during the innate immune response of Drosophila melanogaster Journal Article

J Innate Immun, 3 (1), pp. 52–64, 2011, ISSN: 1662-8128.

Abstract | Links | BibTeX | Tags: bioinformatic, DNA, Evolution, Gene Expression Regulation, Hemocytes, Immunity, In Situ Hybridization, Innate, Molecular, Mutation, Phylogeny, Sequence Analysis

36.

Lee, Kwang-Zin; Ferrandon, Dominique

Negative regulation of immune responses on the fly Journal Article

EMBO J., 30 (6), pp. 988–990, 2011, ISSN: 1460-2075.

Links | BibTeX | Tags: *Gene Expression Regulation, *Homeostasis, Bacteria, Bacteria/*immunology, Biological, Drosophila melanogaster/*immunology, Drosophila Proteins/biosynthesis/metabolism, Gene Expression Regulation, Homeostasis, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Kinases/metabolism, Models, NF-kappa B, NF-kappa B/metabolism, ras Proteins, ras Proteins/metabolism, Receptor Protein-Tyrosine Kinases, Receptor Protein-Tyrosine Kinases/metabolism

2009

Journal Articles

35.

Hetru, Charles; Hoffmann, Jules A

NF-kappaB in the immune response of Drosophila Journal Article

Cold Spring Harb Perspect Biol, 1 (6), pp. a000232, 2009, ISSN: 1943-0264.

Abstract | Links | BibTeX | Tags: Bacteria, Fungi, Gene Expression Regulation, NF-kappa B

34.

Kemp, Cordula; Imler, Jean-Luc

Antiviral immunity in drosophila Journal Article

Current Opinion in Immunology, 21 (1), pp. 3–9, 2009, ISSN: 1879-0372.

Abstract | Links | BibTeX | Tags: Argonaute Proteins, Caspases, DEAD-box RNA Helicases, Evolution, Gene Expression Regulation, Host-Pathogen Interactions, Membrane Proteins, Molecular, Nuclear Proteins, Ribonuclease III, RNA, RNA Helicases, RNA Interference, RNA Virus Infections, RNA Viruses, RNA-Induced Silencing Complex, Viral, Virulence

2008

Journal Articles

33.

Deddouche, Safia; Matt, Nicolas ; Budd, Aidan ; Mueller, Stefanie ; Kemp, Cordula ; Galiana-Arnoux, Delphine ; Dostert, Catherine ; Antoniewski, Christophe ; Hoffmann, Jules A; Imler, Jean-Luc

The DExD/Ħ-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila Journal Article

Nature Immunology, 9 (12), pp. 1425–1432, 2008, ISSN: 1529-2916.

Abstract | Links | BibTeX | Tags: Amino Acid, Electrophoresis, Fat Body, Gene Expression Regulation, Genetic, Genetically Modified, Humans, Phylogeny, Polyacrylamide Gel, Reverse Transcriptase Polymerase Chain Reaction, Ribonuclease III, RNA Helicases, Sequence Homology, Transcription, Virus Diseases

32.

Roetzer, Andreas; Gregori, Christa; Jennings, Ann Marie; Quintin, Jessica; Ferrandon, Dominique; Butler, Geraldine; Kuchler, Karl; Ammerer, Gustav; Schüller, Christoph

Candida glabrata environmental stress response involves Saccharomyces cerevisiae Msn2/4 orthologous transcription factors Journal Article

Mol. Microbiol., 69 (3), pp. 603–620, 2008, ISSN: 1365-2958.

Abstract | Links | BibTeX | Tags: Candida glabrata, Candidiasis, DNA-Binding Proteins, Fungal, Fungal Proteins, Gene Expression Profiling, Gene Expression Regulation, Genetic, Humans, Oligonucleotide Array Sequence Analysis, Osmotic Pressure, Regulon, Saccharomyces cerevisiae Proteins, Transcription, Transcription Factors, Virulence, Yeasts

2006

Journal Articles

31.

Frolet, Cécile; Thoma, Martine; Blandin, Stéphanie A; Hoffmann, Jules A; Levashina, Elena A

Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei Journal Article

Immunity, 25 (4), pp. 677–685, 2006, ISSN: 1074-7613.

Abstract | Links | BibTeX | Tags: Anopheles gambiae, Gene Expression, Gene Expression Regulation, Genes, Immunity, Insect, NF-kappa B, Plasmodium berghei, Telomerase

30.

Pelte, Nadège; Robertson, Andrew S; Zou, Zhen; Belorgey, Didier; Dafforn, Timothy R; Jiang, Haobo; Lomas, David; Reichhart, Jean-Marc; Gubb, David

Immune challenge induces N-terminal cleavage of the Drosophila serpin Necrotic Journal Article

Insect Biochem. Mol. Biol., 36 (1), pp. 37–46, 2006, ISSN: 0965-1748.

Abstract | Links | BibTeX | Tags: Gene Expression Regulation, Protein Conformation, Serpins, Signal Transduction

2005

Journal Articles

29.

Royet, Julien; Reichhart, Jean-Marc ; Hoffmann, Jules A

Sensing and signaling during infection in Drosophila Journal Article

Curr. Opin. Immunol., 17 (1), pp. 11–17, 2005, ISSN: 0952-7915.

Abstract | Links | BibTeX | Tags: Antimicrobial Cationic Peptides, Bacterial Infections, Gene Expression Regulation, Genome, Immunity, Innate, Signal Transduction

28.

Imler, Jean-Luc; Bulet, Philippe

Antimicrobial peptides in Drosophila: structures, activities and gene regulation Journal Article

Chemical Immunology and Allergy, 86 , pp. 1–21, 2005, ISSN: 1660-2242.

Abstract | Links | BibTeX | Tags: Antimicrobial Cationic Peptides, Defensins, Gene Expression Regulation, Genes, Glycopeptides, Immunity, Innate, Insect, Insect Proteins, Molecular Structure, Signal Transduction

2004

Journal Articles

27.

Ferrandon, Dominique; Imler, Jean-Luc; Hoffmann, Jules A

Sensing infection in Drosophila: Toll and beyond Journal Article

Semin Immunol, 16 , pp. 43–53, 2004, ISSN: 1044-5323.

Abstract | BibTeX | Tags: Carrier Proteins/chemistry/immunology/physiology, Cell Surface/immunology/*physiology, Drosophila Proteins/chemistry/immunology/*physiology, Drosophila/genetics/*immunology/microbiology, Fungi/immunology, Gene Expression Regulation, Gram-Negative Bacterial Infections/immunology, Gram-Positive Bacterial Infections/immunology, Immunological, Insect Proteins/chemistry/immunology/physiology, Models, Non-U.S. Gov't, Receptors, Signal Transduction/immunology/physiology, Support

2003

Journal Articles

26.

Luna, C; Hoa, N T; Zhang, J; Kanzok, S M; Brown, S E; Imler, Jean-Luc; Knudson, D L; Zheng, L

Characterization of three Toll-like genes from mosquito Aedes aegypti Journal Article

Insect Molecular Biology, 12 (1), pp. 67–74, 2003, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Aedes, Base Sequence, Cell Surface, Chimera, Cloning, Developmental, Female, Gene Expression Regulation, Genetic, Insect Proteins, Male, Messenger, Models, Molecular, Mutagenesis, Promoter Regions, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Sequence Alignment, Signal Transduction, Site-Directed, Transfection

25.

Kambris, Zakaria; Bilak, Hana; D'Alessandro, Rosalba; Belvin, Marcia; Imler, Jean-Luc; Capovilla, Maria

DmMyD88 controls dorsoventral patterning of the Drosophila embryo Journal Article

EMBO reports, 4 (1), pp. 64–69, 2003, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Alleles, Antigens, Base Sequence, Cell Surface, Complementary, Developmental, Differentiation, DNA, DNA Transposable Elements, Egg Proteins, Embryo, Exons, Female, Gene Expression Regulation, Genetically Modified, Genotype, Immunity, Immunologic, Innate, Insertional, Male, Messenger, Morphogenesis, Mutagenesis, Myeloid Differentiation Factor 88, Nonmammalian, Oocytes, Protein Biosynthesis, Protein Structure, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transducing, Tertiary, Toll-Like Receptors, Zygote

2002

Journal Articles

24.

Naitza, Silvia; Rossé, Carine ; Kappler, Christine ; Georgel, Philippe ; Belvin, Marcia ; Gubb, David ; Camonis, Jacques ; Hoffmann, Jules A; Reichhart, Jean-Marc

The Drosophila immune defense against gram-negative infection requires the death protein dFADD Journal Article

Immunity, 17 (5), pp. 575–581, 2002, ISSN: 1074-7613.

Abstract | BibTeX | Tags: Adaptor Proteins, Carrier Proteins, Fas-Associated Death Domain Protein, Gene Expression Regulation, Gram-Negative Bacterial Infections, Immunity, Signal Transducing, Signal Transduction

23.

Christophides, George K; Zdobnov, Evgeny; Barillas-Mury, Carolina; Birney, Ewan; Blandin, Stephanie A; Blass, Claudia; Brey, Paul T; Collins, Frank H; Danielli, Alberto; Dimopoulos, George; Hetru, Charles; Hoa, Ngo T; Hoffmann, Jules A; Kanzok, Stefan M; Letunic, Ivica; Levashina, Elena A; Loukeris, Thanasis G; Lycett, Gareth; Meister, Stephan; Michel, Kristin; Moita, Luis F; Müller, Hans-Michael; Osta, Mike A; Paskewitz, Susan M; Reichhart, Jean-Marc; Rzhetsky, Andrey; Troxler, Laurent; Vernick, Kenneth D; Vlachou, Dina; Volz, Jennifer; von Mering, Christian; Xu, Jiannong; Zheng, Liangbiao; Bork, Peer; Kafatos, Fotis C

Immunity-related genes and gene families in Anopheles gambiae Journal Article

Science, 298 (5591), pp. 159–165, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Alternative Splicing, Anopheles, Apoptosis, Bacteria, bioinformatic, Catechol Oxidase, Computational Biology, Enzyme Precursors, Gene Expression Regulation, Genes, Genetic, Genome, Immunity, Innate, Insect, Insect Proteins, Multigene Family, Peptides, Phylogeny, Plasmodium, Protein Structure, Selection, Serine Endopeptidases, Serpins, Signal Transduction, Tertiary

22.

Ligoxygakis, Petros; Pelte, Nadège ; Hoffmann, Jules A; Reichhart, Jean-Marc

Activation of Drosophila Toll during fungal infection by a blood serine protease Journal Article

Science, 297 (5578), pp. 114–116, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Cell Surface, Chromosome Mapping, Escherichia coli, Female, Gene Expression Regulation, Genes, Gram-Positive Cocci, Hemolymph, Hypocreales, Insect, Insect Proteins, Male, Mutation, Protein Sorting Signals, Protein Structure, Receptors, Serine Endopeptidases, Tertiary, Toll-Like Receptors

21.

Ligoxygakis, Petros; Bulet, Philippe; Reichhart, Jean-Marc

Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila Journal Article

EMBO Rep., 3 (7), pp. 666–673, 2002, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Cell Adhesion Molecules, Fat Body, Gene Expression Regulation, Genes, Immunohistochemistry, Immunologic, Insect, Insect Proteins, Larva, Mass, Matrix-Assisted Laser Desorption-Ionization, Membrane Proteins, Receptors, Reporter, Spectrometry, Transgenes

20.

Tauszig-Delamasure, Servane; Bilak, Hana ; Capovilla, Maria ; Hoffmann, Jules A; Imler, Jean-Luc

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections Journal Article

Nature Immunology, 3 (1), pp. 91–97, 2002, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Amino Acid, Antigens, Antimicrobial Cationic Peptides, Cell Surface, Chromosome Mapping, Differentiation, Disease Susceptibility, Enterococcus faecalis, Epistasis, Escherichia coli, Female, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Gram-Negative Bacteria, Hypocreales, Immunologic, Insect, Insect Proteins, Membrane Glycoproteins, Micrococcus luteus, Myeloid Differentiation Factor 88, Protein Structure, Protein-Serine-Threonine Kinases, Receptors, Recombinant Fusion Proteins, Sequence Alignment, Sequence Homology, Signal Transducing, Tertiary, Toll-Like Receptors, Transfection

2001

Journal Articles

19.

Irving, Phil; Troxler, Laurent; Heuer, Timothy S; Belvin, Marcia; Kopczynski, Casey; Reichhart, Jean-Marc; Hoffmann, Jules A; Hetru, Charles

A genome-wide analysis of immune responses in Drosophila Journal Article

Proc. Natl. Acad. Sci. U.S.A., 98 (26), pp. 15119–15124, 2001, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: bioinformatic, Gene Expression Regulation, Genome, Gram-Negative Bacteria, Male, Oligonucleotide Array Sequence Analysis, Signal Transduction

2000

Journal Articles

18.

Rutschmann, Sophie; Jung, Alain C; Zhou, R; Silverman, N; Hoffmann, Jules A; Ferrandon, Dominique

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response Journal Article

Nat. Immunol., 1 (4), pp. 342–347, 2000, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: Antigens, Bacterial, Cell Surface, Gene Expression Regulation, I-kappa B Kinase, Immunity, Innate, Insect Proteins, Membrane Glycoproteins, Protein-Serine-Threonine Kinases, Receptors, Signal Transduction, Toll-Like Receptors, Transcription Factors

17.

Basset, A; Khush, R S; Braun, A; Gardan, L; Boccard, F; Hoffmann, Jules A; Lemaitre, Bruno

The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response Journal Article

Proc. Natl. Acad. Sci. U.S.A., 97 (7), pp. 3376–3381, 2000, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: Bacterial, Gene Expression Regulation, Genetically Modified, Insect Proteins, Larva, Pectobacterium carotovorum

16.

Imler, Jean-Luc; Hoffmann, Jules A

Signaling mechanisms in the antimicrobial host defense of Drosophila Journal Article

Current Opinion in Microbiology, 3 (1), pp. 16–22, 2000, ISSN: 1369-5274.

Abstract | BibTeX | Tags: Anti-Infective Agents, Cell Surface, Gene Expression Regulation, Genes, Insect, Insect Proteins, Membrane Glycoproteins, Receptors, Signal Transduction, Toll-Like Receptors

15.

Imler, Jean-Luc; Hoffmann, Jules A

Toll and Toll-like proteins: an ancient family of receptors signaling infection Journal Article

Reviews in Immunogenetics, 2 (3), pp. 294–304, 2000, ISSN: 1398-1714.

Abstract | BibTeX | Tags: Adaptor Proteins, Antigens, Autoantigens, CD14, Cell Adhesion Molecules, Cell Surface, Differentiation, DNA-Binding Proteins, Gene Expression Regulation, I-kappa B Proteins, Immunity, Immunologic, Infection, Innate, Insect Proteins, Interleukin-1 Receptor-Associated Kinases, Knockout, Larva, Lipopolysaccharides, Mammals, MAP Kinase Signaling System, Membrane Glycoproteins, Membrane Proteins, Mice, Multigene Family, Myeloid Differentiation Factor 88, NF-kappa B, Peptidoglycan, Phosphorylation, Post-Translational, Protein Kinases, Protein Processing, Protein Structure, Receptors, Recombinant Fusion Proteins, Signal Transducing, Signal Transduction, Teichoic Acids, Tertiary, Toll-Like Receptor 4, Toll-Like Receptor 5, Toll-Like Receptor 6, Toll-Like Receptor 9, Toll-Like Receptors, Ubiquitins

1999

Journal Articles

14.

Manfruelli, P; Reichhart, Jean-Marc ; Steward, R; Hoffmann, Jules A; Lemaitre, Bruno

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF Journal Article

EMBO J., 18 (12), pp. 3380–3391, 1999, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Anti-Infective Agents, Cell Surface, Clone Cells, DNA-Binding Proteins, Fat Body, Female, Gene Expression Regulation, Genes, Insect, Insect Proteins, Larva, Male, Membrane Glycoproteins, Mosaicism, Mutation, Nuclear Proteins, Phosphoproteins, Receptors, Reporter, Signal Transduction, Toll-Like Receptors, Transcription Factors

1998

Journal Articles

13.

Ferrandon, Dominique; Jung, Alain C; Criqui, M; Lemaitre, Bruno; Uttenweiler-Joseph, S; Michaut, Lydia; Reichhart, Jean-Marc; Hoffmann, Jules A

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway Journal Article

EMBO J., 17 (5), pp. 1217–1227, 1998, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Bacteria, Cell Surface, Developmental, Digestive System, Epithelium, Fat Body, Female, Fungal, Gene Expression Regulation, Genes, Green Fluorescent Proteins, Insect Proteins, Larva, Luminescent Proteins, Male, Membrane Glycoproteins, Organ Specificity, Receptors, Reporter, Respiratory System, Spores, Toll-Like Receptors, Trachea, Transgenes

12.

Nicolas, E; Reichhart, Jean-Marc ; Hoffmann, Jules A; Lemaitre, Bruno

In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila Journal Article

J. Biol. Chem., 273 (17), pp. 10463–10469, 1998, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Cell Surface, DNA-Binding Proteins, Gene Expression Regulation, Insect Proteins, Larva, Membrane Glycoproteins, Phosphoproteins, Proto-Oncogene Proteins, Receptors, Signal Transduction, Toll-Like Receptors, Transcription Factor RelB, Transcription Factors

11.

Levashina, Elena A; Ohresser, S; Lemaitre, Bruno; Imler, Jean-Luc

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin Journal Article

Journal of Molecular Biology, 278 (3), pp. 515–527, 1998, ISSN: 0022-2836.

Abstract | Links | BibTeX | Tags: Anti-Infective Agents, Antimicrobial Cationic Peptides, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Glycopeptides, Insect, Insect Proteins, Larva, Molecular, Mutation, Peptides, Promoter Regions, Recombinant Fusion Proteins, Reporter, Restriction Mapping, Transcription

1997

Journal Articles

10.

Meister, Marie; Lemaitre, Bruno; Hoffmann, Jules A

Antimicrobial peptide defense in Drosophila Journal Article

Bioessays, 19 (11), pp. 1019–1026, 1997, ISSN: 0265-9247.

Abstract | Links | BibTeX | Tags: Anti-Infective Agents, Gene Expression Regulation, Genetic, Insect Proteins, Models, Peptides, Promoter Regions, Signal Transduction

1996

Journal Articles

9.

Gross, I; Georgel, Philippe ; Kappler, Christine ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immunity: a comparative analysis of the Rel proteins dorsal and Dif in the induction of the genes encoding diptericin and cecropin Journal Article

Nucleic Acids Res., 24 (7), pp. 1238–1245, 1996, ISSN: 0305-1048.

Abstract | BibTeX | Tags: Antimicrobial Cationic Peptides, Base Sequence, DNA Primers, DNA-Binding Proteins, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, NF-kappa B, Nuclear Proteins, Peptides, Phosphoproteins, Transcription, Transcription Factors, Transcriptional Activation

1995

Journal Articles

8.

Lemaitre, Bruno; Kromer-Metzger, E; Michaut, Lydia ; Nicolas, E; Meister, Marie ; Georgel, Philippe ; Reichhart, Jean-Marc ; Hoffmann, Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

Proc. Natl. Acad. Sci. U.S.A., 92 (21), pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, Insect, Insect Hormones, Insect Proteins, Male, Mutation, Mycoses, Nucleic Acid, Peptides, Protein Binding, Recessive, Regulatory Sequences, Reporter, Survival Analysis

7.

Hoffmann, Jules A

Innate immunity of insects Journal Article

Curr. Opin. Immunol., 7 (1), pp. 4–10, 1995, ISSN: 0952-7915.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Blood Proteins, Cellular, Defensins, Gene Expression Regulation, Immunity, Innate, Insects, Peptides

6.

Lemaitre, Bruno; Meister, Marie ; Govind, S; Georgel, Philippe ; Steward, R; Reichhart, Jean-Marc ; Hoffmann, Jules A

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila Journal Article

EMBO J., 14 (3), pp. 536–545, 1995, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Anti-Infective Agents, Antimicrobial Cationic Peptides, Biological Transport, Cell Nucleus, Cell Surface, DNA-Binding Proteins, Fat Body, Gene Expression Regulation, Genetic, Immunity, Immunohistochemistry, Insect Hormones, Insect Proteins, Melanins, Membrane Glycoproteins, Mutation, Neoplasms, Nuclear Proteins, Phosphoproteins, Receptors, Signal Transduction, Toll-Like Receptors, Transcription, Transcription Factors

1994

Journal Articles

5.

Meister, Marie; Braun, A; Kappler, Christine ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter Journal Article

EMBO J., 13 (24), pp. 5958–5966, 1994, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Infective Agents, Base Sequence, beta-Galactosidase, DNA Mutational Analysis, Female, Gene Expression Regulation, Genetic, Genetically Modified, Germ Cells, Insect Hormones, Insect Proteins, Male, Models, Nucleic Acid, Promoter Regions, Recombinant Fusion Proteins, Repetitive Sequences, Transformation

1993

Journal Articles

4.

Kappler, Christine; Meister, Marie ; Lagueux, Marie ; Gateff, E; Hoffmann, Jules A; Reichhart, Jean-Marc

Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila Journal Article

EMBO J., 12 (4), pp. 1561–1568, 1993, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Base Sequence, Cloning, Gene Expression Regulation, Genes, Genetic, Genetically Modified, Insect, Insect Hormones, Insect Proteins, Lipopolysaccharides, Messenger, Molecular, NF-kappa B, Nucleic Acid, Oligodeoxyribonucleotides, Promoter Regions, Regulatory Sequences, RNA, Transfection

1992

Journal Articles

3.

Reichhart, Jean-Marc; Meister, Marie ; Dimarcq, Jean-Luc ; Zachary, Daniel ; Hoffmann, Danièle ; Ruiz, C; Richards, G; Hoffmann, Jules A

Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter Journal Article

EMBO J., 11 (4), pp. 1469–1477, 1992, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Acute-Phase Proteins, Adipose Tissue, Base Sequence, beta-Galactosidase, Embryo, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, Mammals, Nonmammalian, Oligodeoxyribonucleotides, Promoter Regions, Recombinant Fusion Proteins, Restriction Mapping

1990

Journal Articles

2.

Hoffmann, Jules A; Hoffmann, Danièle

The inducible antibacterial peptides of dipteran insects Journal Article

Res. Immunol., 141 (9), pp. 910–918, 1990, ISSN: 0923-2494.

BibTeX | Tags: Antimicrobial Cationic Peptides, Defensins, Diptera, Gene Expression Regulation, Genetic, Insect Hormones, Insect Proteins, Nucleic Acid, Proteins, Sequence Homology, Transcription

1989

Journal Articles

1.

Reichhart, Jean-Marc; Essrich, M; Dimarcq, Jean-Luc ; Hoffmann, Danièle ; Hoffmann, Jules A; Lagueux, Marie

Insect immunity. Isolation of cDNA clones corresponding to diptericin, an inducible antibacterial peptide from Phormia terranovae (Diptera). Transcriptional profiles during immunization Journal Article

Eur. J. Biochem., 182 (2), pp. 423–427, 1989, ISSN: 0014-2956.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Bacterial Proteins, Base Sequence, Blotting, Diptera, DNA, Endoribonucleases, Enterobacter, Enterobacteriaceae, Gene Expression Regulation, Genes, Genetic, Insect Hormones, Insect Proteins, Messenger, MHC Class II, Northern, Ribonuclease H, RNA, Transcription