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2016

Journal Articles

17.

Lamiable, Olivier; Kellenberger, Christine; Kemp, Cordula; Troxler, Laurent; Pelte, Nadège; Boutros, Michael; Marques, Joao Trindade; Daeffler, Laurent; Hoffmann, Jules A; Roussel, Alain; Imler, Jean-Luc

Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila Journal Article

PNAS, 113 (3), pp. 698–703, 2016, ISSN: 0027-8424, 1091-6490.

Abstract | Links | BibTeX | Tags: antiviral immunity, bioinformatic, cytokine, Edin, Sindbis Virus, virokine

2015

Journal Articles

16.

Veillard, Florian; Troxler, Laurent; Reichhart, Jean-Marc

Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation Journal Article

Biochimie, 122 , pp. 255-269, 2015, ISBN: 0300-9084.

Abstract | Links | BibTeX | Tags: bioinformatic, Chymotrypsin, clip domain, Immunity, Insect, Melanization, Serine Proteases, Serpin, Toll

15.

Volohonsky, Gloria; Terenzi, Olivier; Soichot, Julien; Naujoks, Daniel A; Nolan, Tony; Windbichler, Nikolai; Kapps, Delphine; Smidler, Andie L; Vittu, Anaïs; Costa, Giulia; Steinert, Stefanie; Levashina, Elena A; Blandin, Stéphanie A; Marois, Eric

Tools for Anopheles gambiae Transgenesis Journal Article

G3 (Bethesda), 5 (6), pp. 1151-63, 2015.

Abstract | Links | BibTeX | Tags: Anopheles gambiae, bioinformatic, transgenesis

2014

Journal Articles

14.

Chtarbanova, Stanislava; Lamiable, Olivier; Lee, Kwang-Zin; Galiana, Delphine; Troxler, Laurent; Meignin, Carine; Hetru, Charles; Hoffmann, Jules A; Daeffler, Laurent; Imler, Jean-Luc

Drosophila C virus systemic infection leads to intestinal obstruction Journal Article

Journal of Virology, 88 (24), pp. 14057–14069, 2014, ISSN: 1098-5514.

Abstract | Links | BibTeX | Tags: bioinformatic, Dicistroviridae, Female, Gastrointestinal Tract, Gene Expression Profiling, Intestinal Obstruction, Muscle, Nodaviridae, Sindbis Virus, Smooth, Viral Tropism

13.

Bonnay, François; Nguyen, Xuan-Hung; Cohen-Berros, Eva; Troxler, Laurent; Batsche, Eric; Camonis, Jacques; Takeuchi, Osamu; Reichhart, Jean-Marc; Matt, Nicolas

Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling Journal Article

EMBO J., 33 (20), pp. 2349–2362, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: bioinformatic, Cell Cycle Proteins, Chromatin Assembly and Disassembly, chromatin remodeling, DNA-Binding Proteins, Female, Genetic, Immunity, Innate, Innate immune response, Male, Mutation, NF-kappa B, NF‐κB, Promoter Regions, Proteomics, Trans-Activators, Transcription Factors, Transcriptional Activation, Two-Hybrid System Techniques

2013

Journal Articles

12.

Kemp, Cordula; Mueller, Stefanie ; Goto, Akira ; Barbier, Vincent ; Paro, Simona ; Bonnay, François ; Dostert, Catherine ; Troxler, Laurent ; Hetru, Charles ; Meignin, Carine ; Pfeffer, Sébastien ; Hoffmann, Jules A; Imler, Jean-Luc

Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila Journal Article

Journal of Immunology (Baltimore, Md.: 1950), 190 (2), pp. 650–658, 2013, ISSN: 1550-6606.

Abstract | Links | BibTeX | Tags: Alphavirus, Alphavirus Infections, bioinformatic, DNA Virus Infections, Gene Expression Regulation, Genetically Modified, Janus Kinases, Male, Nodaviridae, Ribonuclease III, RNA Helicases, RNA Interference, RNA Virus Infections, Transcription Factors

2011

Journal Articles

11.

Aoun, Richard Bou; Hetru, Charles; Troxler, Laurent; Doucet, Daniel; Ferrandon, Dominique; Matt, Nicolas

Analysis of thioester-containing proteins during the innate immune response of Drosophila melanogaster Journal Article

J Innate Immun, 3 (1), pp. 52–64, 2011, ISSN: 1662-8128.

Abstract | Links | BibTeX | Tags: bioinformatic, DNA, Evolution, Gene Expression Regulation, Hemocytes, Immunity, In Situ Hybridization, Innate, Molecular, Mutation, Phylogeny, Sequence Analysis

2010

Journal Articles

10.

Gubb, David; Sanz-Parra, Arantza; Barcena, Laura; Troxler, Laurent; Fullaondo, Ane

Protease inhibitors and proteolytic signalling cascades in insects Journal Article

Biochimie, 92 (12), pp. 1749–1759, 2010, ISSN: 1638-6183.

Abstract | Links | BibTeX | Tags: bioinformatic, Insect Proteins, Insects, Macroglobulins, Peptide Hydrolases, Protease Inhibitors, Serpins, Signal Transduction

9.

Mueller, Stefanie; Gausson, Valérie ; Vodovar, Nicolas ; Deddouche, Safia ; Troxler, Laurent ; Perot, Jonathan ; Pfeffer, Sébastien ; Hoffmann, Jules A; Saleh, Maria-Carla ; Imler, Jean-Luc

RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila Journal Article

Proceedings of the National Academy of Sciences of the United States of America, 107 (45), pp. 19390–19395, 2010, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: bioinformatic, Cell Line, Double-Stranded, Genome, Immunity, Innate, Insect Vectors, RNA, RNA Interference, RNA Viruses, Vesiculovirus, Viral

2009

Journal Articles

8.

Garrett, Matthew; Fullaondo, Ane; Troxler, Laurent; Micklem, Gos; Gubb, David

Identification and analysis of serpin-family genes by homology and synteny across the 12 sequenced Drosophilid genomes Journal Article

BMC Genomics, 10 , pp. 489, 2009, ISSN: 1471-2164.

Abstract | Links | BibTeX | Tags: bioinformatic, Comparative Genomic Hybridization, Conserved Sequence, DNA, Drosophilidae, Evolution, Genome, Insect, Molecular, Multigene Family, Sequence Alignment, Sequence Analysis, Serpins, Synteny

2007

Incollections

7.

Gubb, David; Robertson, Andrew S; Troxler, Laurent; Reichhart, Jean-Marc

Drosophila Serpins: Regulatory Cascades in Innate Immunity and Morphogenesis Incollection

Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity, pp. 207–227, Silverman GA and Lomas DA, London UK, 2007.

BibTeX | Tags: bioinformatic, innate immunity, Morphogenesis, regulatory Cascades, Serpins

2005

Journal Articles

6.

Irving, Phil; Ubeda, Jean-Michel; Doucet, Daniel; Troxler, Laurent; Lagueux, Marie; Zachary, Daniel; Hoffmann, Jules A; Hetru, Charles; Meister, Marie

New insights into Drosophila larval haemocyte functions through genome-wide analysis Journal Article

Cell. Microbiol., 7 (3), pp. 335–350, 2005, ISSN: 1462-5814.

Abstract | Links | BibTeX | Tags: bioinformatic, Catechol Oxidase, Cell Lineage, Enzyme Precursors, Escherichia coli, Fat Body, Gene Expression Profiling, Genome, Hemocytes, Integrin alpha Chains, Integrins, Larva, Micrococcus luteus

5.

Dostert, Catherine; Jouanguy, Emmanuelle ; Irving, Phil ; Troxler, Laurent ; Galiana-Arnoux, Delphine ; Hetru, Charles ; Hoffmann, Jules A; Imler, Jean-Luc

The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila Journal Article

Nature Immunology, 6 (9), pp. 946–953, 2005, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: bioinformatic, DNA-Binding Proteins, Genetic, Genetically Modified, Insect Viruses, Janus Kinase 1, Male, Oligonucleotide Array Sequence Analysis, Promoter Regions, Protein-Tyrosine Kinases, Signal Transduction, STAT1 Transcription Factor, Trans-Activators

2004

Journal Articles

4.

Irving, Phil; Troxler, Laurent; Hetru, Charles

Is innate enough? The innate immune response in Drosophila Journal Article

C. R. Biol., 327 (6), pp. 557–570, 2004, ISSN: 1631-0691.

Abstract | BibTeX | Tags: bioinformatic, Immunity, Innate, Signal Transduction

2003

Journal Articles

3.

Hetru, Charles; Troxler, Laurent; Hoffmann, Jules A

Drosophila melanogaster antimicrobial defense Journal Article

J. Infect. Dis., 187 Suppl 2 , pp. S327–334, 2003, ISSN: 0022-1899.

Abstract | Links | BibTeX | Tags: Animal, Bacterial Infections, bioinformatic, Immunity, Innate, Mycoses, Parasitic Diseases, Peptides, Signal Transduction

2002

Journal Articles

2.

Christophides, George K; Zdobnov, Evgeny; Barillas-Mury, Carolina; Birney, Ewan; Blandin, Stephanie A; Blass, Claudia; Brey, Paul T; Collins, Frank H; Danielli, Alberto; Dimopoulos, George; Hetru, Charles; Hoa, Ngo T; Hoffmann, Jules A; Kanzok, Stefan M; Letunic, Ivica; Levashina, Elena A; Loukeris, Thanasis G; Lycett, Gareth; Meister, Stephan; Michel, Kristin; Moita, Luis F; Müller, Hans-Michael; Osta, Mike A; Paskewitz, Susan M; Reichhart, Jean-Marc; Rzhetsky, Andrey; Troxler, Laurent; Vernick, Kenneth D; Vlachou, Dina; Volz, Jennifer; von Mering, Christian; Xu, Jiannong; Zheng, Liangbiao; Bork, Peer; Kafatos, Fotis C

Immunity-related genes and gene families in Anopheles gambiae Journal Article

Science, 298 (5591), pp. 159–165, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Alternative Splicing, Anopheles, Apoptosis, Bacteria, bioinformatic, Catechol Oxidase, Computational Biology, Enzyme Precursors, Gene Expression Regulation, Genes, Genetic, Genome, Immunity, Innate, Insect, Insect Proteins, Multigene Family, Peptides, Phylogeny, Plasmodium, Protein Structure, Selection, Serine Endopeptidases, Serpins, Signal Transduction, Tertiary

2001

Journal Articles

1.

Irving, Phil; Troxler, Laurent; Heuer, Timothy S; Belvin, Marcia; Kopczynski, Casey; Reichhart, Jean-Marc; Hoffmann, Jules A; Hetru, Charles

A genome-wide analysis of immune responses in Drosophila Journal Article

Proc. Natl. Acad. Sci. U.S.A., 98 (26), pp. 15119–15124, 2001, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: bioinformatic, Gene Expression Regulation, Genome, Gram-Negative Bacteria, Male, Oligonucleotide Array Sequence Analysis, Signal Transduction