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2014

Journal Articles

10.

Tartey, Sarang; Matsushita, Kazufumi ; Vandenbon, Alexis ; Ori, Daisuke ; Imamura, Tomoko ; Mino, Takashi ; Standley, Daron M; Hoffmann, Jules A; Reichhart, Jean-Marc ; Akira, Shizuo ; Takeuchi, Osamu

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex Journal Article

EMBO J., 33 (20), pp. 2332–2348, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Cell Nucleus, Chromatin Assembly and Disassembly, chromatin remodeling, Chromosomal Proteins, cytokine, Cytokines, Female, Gene Expression Regulation, gene regulation, Genetic, Humans, Immunity, Innate, innate immunity, Knockout, Listeria monocytogenes, Macrophages, Male, Mice, Multiprotein Complexes, Non-Histone, Nuclear Proteins, Promoter Regions, Protein Binding, Repressor Proteins, Sequence Deletion, Signal Transducing, Transcriptional Activation

2011

Journal Articles

9.

Eleftherianos, Ioannis; Won, Sungyong ; Chtarbanova, Stanislava ; Squiban, Barbara ; Ocorr, Karen ; Bodmer, Rolf ; Beutler, Bruce ; Hoffmann, Jules A; Imler, Jean-Luc

ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections Journal Article

Proceedings of the National Academy of Sciences of the United States of America, 108 (29), pp. 12024–12029, 2011, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags: Heart, HeLa Cells, Humans, Immunity, Immunoblotting, Inbred C57BL, Innate, KATP Channels, Mice, Nodaviridae, Pinacidil, Reverse Transcriptase Polymerase Chain Reaction, RNA Interference, Tolbutamide, Viral Load, Viremia

8.

Ogawa, Michinaga; Yoshikawa, Yuko; Kobayashi, Taira; Mimuro, Hitomi; Fukumatsu, Makoto; Kiga, Kotaro; Piao, Zhenzi; Ashida, Hiroshi; Yoshida, Mitsutaka; Kakuta, Shigeru; Koyama, Tomohiro; Goto, Yoshiyuki; Nagatake, Takahiro; Nagai, Shinya; Kiyono, Hiroshi; Kawalec, Magdalena; Reichhart, Jean-Marc; Sasakawa, Chihiro

A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens Journal Article

Cell Host Microbe, 9 (5), pp. 376–389, 2011, ISSN: 1934-6069.

Abstract | Links | BibTeX | Tags: Autophagy, Biological, Cells, Cultured, Membrane Proteins, Mice, Microtubule-Associated Proteins, Models, Phagosomes, Protein Interaction Mapping, Shigella, Two-Hybrid System Techniques

2010

Journal Articles

7.

Silverman, Gary A; Whisstock, James C; Bottomley, Stephen P; Huntington, James A; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Bird, Phillip I

Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems Journal Article

J. Biol. Chem., 285 (32), pp. 24299–24305, 2010, ISSN: 1083-351X.

Abstract | Links | BibTeX | Tags: Biological, Caenorhabditis elegans, Cell Death, Cell Differentiation, Cell Survival, Homeostasis, Humans, Immunity, Innate, Mice, Models, Phenotype, Serpins, Transgenes, Transgenic

6.

Pospisilik, Andrew J; Schramek, Daniel; Schnidar, Harald; Cronin, Shane J F; Nehme, Nadine T; Zhang, Xiaoyun; Knauf, Claude; Cani, Patrice D; Aumayr, Karin; Todoric, Jelena; Bayer, Martina; Haschemi, Arvand; Puviindran, Vijitha; Tar, Krisztina; Orthofer, Michael; Neely, Gregory G; Dietzl, Georg; Manoukian, Armen; Funovics, Martin; Prager, Gerhard; Wagner, Oswald; Ferrandon, Dominique; Aberger, Fritz; Hui, Chi-chung; Esterbauer, Harald; Penninger, Josef M

Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate Journal Article

Cell, 140 (1), pp. 148–160, 2010, ISSN: 1097-4172.

Abstract | Links | BibTeX | Tags: Adipocytes, Adipogenesis, Brown, Brown/metabolism, Cyclic AMP, Cyclic AMP/metabolism, Drosophila Proteins/*metabolism, Glucocorticoids, Glucocorticoids/metabolism, Hedgehog Proteins, Hedgehog Proteins/*metabolism, Humans, Knockout, Mice, Muscle Cells, Muscle Cells/metabolism, Obesity, Obesity/*genetics, Repressor Proteins, Repressor Proteins/genetics, White, White/metabolism

2008

Journal Articles

5.

Goto, Akira; Matsushita, Kazufumi ; Gesellchen, Viola ; Chamy, Laure El ; Kuttenkeuler, David ; Takeuchi, Osamu ; Hoffmann, Jules A; Akira, Shizuo ; Boutros, Michael ; Reichhart, Jean-Marc

Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice Journal Article

Nat. Immunol., 9 (1), pp. 97–104, 2008, ISSN: 1529-2916.

Abstract | Links | BibTeX | Tags: Cell Line, Embryo, Fibroblasts, Humans, Immunity, Innate, Interleukin-1beta, Mammalian, Mice, NF-kappa B, Nuclear Proteins, Proteins, Signal Transduction, Toll-Like Receptors, Transgenic, Tumor Necrosis Factor-alpha

2007

Journal Articles

4.

Croker, Ben; Crozat, Karine; Berger, Michael; Xia, Yu; Sovath, Sosathya; Schaffer, Lana; Eleftherianos, Ioannis; Imler, Jean-Luc; Beutler, Bruce

ATP-sensitive potassium channels mediate survival during infection in mammals and insects Journal Article

Nature Genetics, 39 (12), pp. 1453–1460, 2007, ISSN: 1546-1718.

Abstract | Links | BibTeX | Tags: ATP-Binding Cassette Transporters, Cloning, Coronary Vessels, Crosses, Ethylnitrosourea, Genetic, Homozygote, Infection, Inwardly Rectifying, KATP Channels, Lipopolysaccharides, Mice, Molecular, Mutagenesis, Potassium Channels, Sulfonylurea Receptors

2004

Journal Articles

3.

Imler, Jean-Luc; Zheng, Liangbiao

Biology of Toll receptors: lessons from insects and mammals Journal Article

Journal of Leukocyte Biology, 75 (1), pp. 18–26, 2004, ISSN: 0741-5400.

Abstract | Links | BibTeX | Tags: Anopheles, Cell Surface, Humans, Membrane Glycoproteins, Mice, Phylogeny, Plant Physiological Phenomena, Receptors, Signal Transduction, Toll-Like Receptor 5, Toll-Like Receptors

2003

Journal Articles

2.

Imler, Jean-Luc; Hoffmann, Jules A

Toll signaling: the TIReless quest for specificity Journal Article

Nature Immunology, 4 (2), pp. 105–106, 2003, ISSN: 1529-2908.

Links | BibTeX | Tags: Cell Surface, Dendritic Cells, Humans, Immunological, Interferon-beta, Membrane Glycoproteins, Mice, Models, Protein Structure, Receptors, Signal Transduction, Tertiary, Toll-Like Receptors

2000

Journal Articles

1.

Imler, Jean-Luc; Hoffmann, Jules A

Toll and Toll-like proteins: an ancient family of receptors signaling infection Journal Article

Reviews in Immunogenetics, 2 (3), pp. 294–304, 2000, ISSN: 1398-1714.

Abstract | BibTeX | Tags: Adaptor Proteins, Antigens, Autoantigens, CD14, Cell Adhesion Molecules, Cell Surface, Differentiation, DNA-Binding Proteins, Gene Expression Regulation, I-kappa B Proteins, Immunity, Immunologic, Infection, Innate, Insect Proteins, Interleukin-1 Receptor-Associated Kinases, Knockout, Larva, Lipopolysaccharides, Mammals, MAP Kinase Signaling System, Membrane Glycoproteins, Membrane Proteins, Mice, Multigene Family, Myeloid Differentiation Factor 88, NF-kappa B, Peptidoglycan, Phosphorylation, Post-Translational, Protein Kinases, Protein Processing, Protein Structure, Receptors, Recombinant Fusion Proteins, Signal Transducing, Signal Transduction, Teichoic Acids, Tertiary, Toll-Like Receptor 4, Toll-Like Receptor 5, Toll-Like Receptor 6, Toll-Like Receptor 9, Toll-Like Receptors, Ubiquitins