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2014

Journal Articles

18.

Bonnay, François; Nguyen, Xuan-Hung; Cohen-Berros, Eva; Troxler, Laurent; Batsche, Eric; Camonis, Jacques; Takeuchi, Osamu; Reichhart, Jean-Marc; Matt, Nicolas

Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling Journal Article

EMBO J., 33 (20), pp. 2349–2362, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: bioinformatic, Cell Cycle Proteins, Chromatin Assembly and Disassembly, chromatin remodeling, DNA-Binding Proteins, Female, Genetic, Immunity, Innate, Innate immune response, Male, Mutation, NF-kappa B, NF‐κB, Promoter Regions, Proteomics, Trans-Activators, Transcription Factors, Transcriptional Activation, Two-Hybrid System Techniques

17.

Tartey, Sarang; Matsushita, Kazufumi ; Vandenbon, Alexis ; Ori, Daisuke ; Imamura, Tomoko ; Mino, Takashi ; Standley, Daron M; Hoffmann, Jules A; Reichhart, Jean-Marc ; Akira, Shizuo ; Takeuchi, Osamu

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex Journal Article

EMBO J., 33 (20), pp. 2332–2348, 2014, ISSN: 1460-2075.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Cell Nucleus, Chromatin Assembly and Disassembly, chromatin remodeling, Chromosomal Proteins, cytokine, Cytokines, Female, Gene Expression Regulation, gene regulation, Genetic, Humans, Immunity, Innate, innate immunity, Knockout, Listeria monocytogenes, Macrophages, Male, Mice, Multiprotein Complexes, Non-Histone, Nuclear Proteins, Promoter Regions, Protein Binding, Repressor Proteins, Sequence Deletion, Signal Transducing, Transcriptional Activation

16.

Amcheslavsky, Alla; Song, Wei; Li, Qi; Nie, Yingchao; Bragatto, Ivan; Ferrandon, Dominique; Perrimon, Norbert; Ip, Tony Y

Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila Journal Article

Cell Rep, 9 (1), pp. 32–39, 2014, ISSN: 2211-1247.

Abstract | Links | BibTeX | Tags: Cell Differentiation, Enterocytes, Enteroendocrine Cells, Female, Homeostasis, Intestines, Male, Stem Cells, Tachykinins

2013

Journal Articles

15.

Kemp, Cordula; Mueller, Stefanie ; Goto, Akira ; Barbier, Vincent ; Paro, Simona ; Bonnay, François ; Dostert, Catherine ; Troxler, Laurent ; Hetru, Charles ; Meignin, Carine ; Pfeffer, Sébastien ; Hoffmann, Jules A; Imler, Jean-Luc

Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila Journal Article

Journal of Immunology (Baltimore, Md.: 1950), 190 (2), pp. 650–658, 2013, ISSN: 1550-6606.

Abstract | Links | BibTeX | Tags: Alphavirus, Alphavirus Infections, bioinformatic, DNA Virus Infections, Gene Expression Regulation, Genetically Modified, Janus Kinases, Male, Nodaviridae, Ribonuclease III, RNA Helicases, RNA Interference, RNA Virus Infections, Transcription Factors

2005

Journal Articles

14.

Dostert, Catherine; Jouanguy, Emmanuelle ; Irving, Phil ; Troxler, Laurent ; Galiana-Arnoux, Delphine ; Hetru, Charles ; Hoffmann, Jules A; Imler, Jean-Luc

The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila Journal Article

Nature Immunology, 6 (9), pp. 946–953, 2005, ISSN: 1529-2908.

Abstract | Links | BibTeX | Tags: bioinformatic, DNA-Binding Proteins, Genetic, Genetically Modified, Insect Viruses, Janus Kinase 1, Male, Oligonucleotide Array Sequence Analysis, Promoter Regions, Protein-Tyrosine Kinases, Signal Transduction, STAT1 Transcription Factor, Trans-Activators

2003

Journal Articles

13.

Thouzeau, Cécile; Maho, Yvon Le; Froget, Guillaume; Sabatier, Laurence; Bohec, Céline Le; Hoffmann, Jules A; Bulet, Philippe

Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus Journal Article

J. Biol. Chem., 278 (51), pp. 51053–51058, 2003, ISSN: 0021-9258.

Abstract | Links | BibTeX | Tags: Antimicrobial Cationic Peptides, Bacteria, beta-Defensins, Birds, Feeding Behavior, Fungi, Gastrointestinal Contents, Male, Mass, Matrix-Assisted Laser Desorption-Ionization, Protein Isoforms, Sequence Alignment, Spectrometry

12.

Luna, C; Hoa, N T; Zhang, J; Kanzok, S M; Brown, S E; Imler, Jean-Luc; Knudson, D L; Zheng, L

Characterization of three Toll-like genes from mosquito Aedes aegypti Journal Article

Insect Molecular Biology, 12 (1), pp. 67–74, 2003, ISSN: 0962-1075.

Abstract | BibTeX | Tags: Aedes, Base Sequence, Cell Surface, Chimera, Cloning, Developmental, Female, Gene Expression Regulation, Genetic, Insect Proteins, Male, Messenger, Models, Molecular, Mutagenesis, Promoter Regions, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Sequence Alignment, Signal Transduction, Site-Directed, Transfection

11.

Kambris, Zakaria; Bilak, Hana; D'Alessandro, Rosalba; Belvin, Marcia; Imler, Jean-Luc; Capovilla, Maria

DmMyD88 controls dorsoventral patterning of the Drosophila embryo Journal Article

EMBO reports, 4 (1), pp. 64–69, 2003, ISSN: 1469-221X.

Abstract | Links | BibTeX | Tags: Adaptor Proteins, Alleles, Antigens, Base Sequence, Cell Surface, Complementary, Developmental, Differentiation, DNA, DNA Transposable Elements, Egg Proteins, Embryo, Exons, Female, Gene Expression Regulation, Genetically Modified, Genotype, Immunity, Immunologic, Innate, Insertional, Male, Messenger, Morphogenesis, Mutagenesis, Myeloid Differentiation Factor 88, Nonmammalian, Oocytes, Protein Biosynthesis, Protein Structure, Receptors, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transducing, Tertiary, Toll-Like Receptors, Zygote

2002

Journal Articles

10.

Ligoxygakis, Petros; Pelte, Nadège ; Hoffmann, Jules A; Reichhart, Jean-Marc

Activation of Drosophila Toll during fungal infection by a blood serine protease Journal Article

Science, 297 (5578), pp. 114–116, 2002, ISSN: 1095-9203.

Abstract | Links | BibTeX | Tags: Cell Surface, Chromosome Mapping, Escherichia coli, Female, Gene Expression Regulation, Genes, Gram-Positive Cocci, Hemolymph, Hypocreales, Insect, Insect Proteins, Male, Mutation, Protein Sorting Signals, Protein Structure, Receptors, Serine Endopeptidases, Tertiary, Toll-Like Receptors

2001

Journal Articles

9.

Irving, Phil; Troxler, Laurent; Heuer, Timothy S; Belvin, Marcia; Kopczynski, Casey; Reichhart, Jean-Marc; Hoffmann, Jules A; Hetru, Charles

A genome-wide analysis of immune responses in Drosophila Journal Article

Proc. Natl. Acad. Sci. U.S.A., 98 (26), pp. 15119–15124, 2001, ISSN: 0027-8424.

Abstract | Links | BibTeX | Tags: bioinformatic, Gene Expression Regulation, Genome, Gram-Negative Bacteria, Male, Oligonucleotide Array Sequence Analysis, Signal Transduction

8.

Georgel, Philippe; Naitza, S; Kappler, Christine ; Ferrandon, Dominique ; Zachary, Daniel ; Swimmer, C; Kopczynski, C; Duyk, G; Reichhart, Jean-Marc ; Hoffmann, Jules A

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis Journal Article

Dev. Cell, 1 (4), pp. 503–514, 2001, ISSN: 1534-5807.

Abstract | BibTeX | Tags: Anti-Infective Agents, Apoptosis, Bacterial Infections, Caspases, Chromosome Mapping, Cysteine Proteinase Inhibitors, DNA Damage, Female, Gene Expression, I-kappa B Kinase, Immunocompromised Host, In Situ Nick-End Labeling, Insect Proteins, Male, Mutation, Phenotype, Protein Structure, Protein-Serine-Threonine Kinases, Tertiary

1999

Journal Articles

7.

Manfruelli, P; Reichhart, Jean-Marc ; Steward, R; Hoffmann, Jules A; Lemaitre, Bruno

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF Journal Article

EMBO J., 18 (12), pp. 3380–3391, 1999, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Anti-Infective Agents, Cell Surface, Clone Cells, DNA-Binding Proteins, Fat Body, Female, Gene Expression Regulation, Genes, Insect, Insect Proteins, Larva, Male, Membrane Glycoproteins, Mosaicism, Mutation, Nuclear Proteins, Phosphoproteins, Receptors, Reporter, Signal Transduction, Toll-Like Receptors, Transcription Factors

1998

Journal Articles

6.

Ferrandon, Dominique; Jung, Alain C; Criqui, M; Lemaitre, Bruno; Uttenweiler-Joseph, S; Michaut, Lydia; Reichhart, Jean-Marc; Hoffmann, Jules A

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway Journal Article

EMBO J., 17 (5), pp. 1217–1227, 1998, ISSN: 0261-4189.

Abstract | Links | BibTeX | Tags: Bacteria, Cell Surface, Developmental, Digestive System, Epithelium, Fat Body, Female, Fungal, Gene Expression Regulation, Genes, Green Fluorescent Proteins, Insect Proteins, Larva, Luminescent Proteins, Male, Membrane Glycoproteins, Organ Specificity, Receptors, Reporter, Respiratory System, Spores, Toll-Like Receptors, Trachea, Transgenes

1995

Journal Articles

5.

Lemaitre, Bruno; Kromer-Metzger, E; Michaut, Lydia ; Nicolas, E; Meister, Marie ; Georgel, Philippe ; Reichhart, Jean-Marc ; Hoffmann, Jules A

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense Journal Article

Proc. Natl. Acad. Sci. U.S.A., 92 (21), pp. 9465–9469, 1995, ISSN: 0027-8424.

Abstract | BibTeX | Tags: Anti-Bacterial Agents, Antimicrobial Cationic Peptides, Bacterial Infections, Base Sequence, Gene Expression Regulation, Genes, Glycopeptides, Insect, Insect Hormones, Insect Proteins, Male, Mutation, Mycoses, Nucleic Acid, Peptides, Protein Binding, Recessive, Regulatory Sequences, Reporter, Survival Analysis

1994

Journal Articles

4.

Fehlbaum, P; Bulet, Philippe; Michaut, L; Lagueux, Marie; Broekaert, W F; Hetru, Charles; Hoffmann, Jules A

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides Journal Article

J. Biol. Chem., 269 (52), pp. 33159–33163, 1994, ISSN: 0021-9258.

Abstract | BibTeX | Tags: Amino Acid, Antifungal Agents, Base Sequence, Cloning, Complementary, DNA, Insect Proteins, Male, Messenger, Microbial Sensitivity Tests, Molecular, Peptide Biosynthesis, Peptides, Plants, Protein Biosynthesis, Protein Precursors, Proteins, RNA, Sequence Homology

3.

Meister, Marie; Braun, A; Kappler, Christine ; Reichhart, Jean-Marc ; Hoffmann, Jules A

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter Journal Article

EMBO J., 13 (24), pp. 5958–5966, 1994, ISSN: 0261-4189.

Abstract | BibTeX | Tags: Anti-Infective Agents, Base Sequence, beta-Galactosidase, DNA Mutational Analysis, Female, Gene Expression Regulation, Genetic, Genetically Modified, Germ Cells, Insect Hormones, Insect Proteins, Male, Models, Nucleic Acid, Promoter Regions, Recombinant Fusion Proteins, Repetitive Sequences, Transformation

1977

Journal Articles

2.

Lagueux, Marie; Hirn, M; Hoffmann, Jules A

Ecdysone during ovarian development in Locusta migratoria Journal Article

J. Insect Physiol., 23 (1), pp. 109–119, 1977, ISSN: 0022-1910.

BibTeX | Tags: Ecdysone, Female, Grasshoppers, Male, Oogenesis, Ovary

1970

Journal Articles

1.

Hoffmann, Jules A

Endocrine regulation of production and differentiation of hemocytes in an orthopteran insect: Locusta migratoria migratoroides Journal Article

Gen. Comp. Endocrinol., 15 (2), pp. 198–219, 1970, ISSN: 0016-6480.

BibTeX | Tags: Biological, Blood Cells, Electrocoagulation, Female, Hemolymph, Insects, Male, Metamorphosis, Microscopy, Neurosecretory Systems, Phase-Contrast